ArticleAmerican journal of medical genetics. Part A2014
Genetic knowledge and attitudes of parents of children with congenital heart defects.
Article in American journal of medical genetics. Part A, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Social determinants of health and outcomes for children and adults with congenital heart disease: a systematic review.Pediatric research · 2021Pooled it
- Integrating preconception carrier screening into public health: lessons learned from a pilot implementation study.Journal of assisted reproduction and genetics · 2026Article
- Verbesserung der interdisziplinären Zusammenarbeit zwischen den Fachgebieten Kinder- und Jugendpsychiatrie, und -psychotherapie sowie Humangenetik - Anregungen aus kinder- und jugendpsychiatrischer Sicht.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2025Article
- Genomic Health Literacy Interventions in Pediatrics: Scoping Review.Journal of medical Internet research · 2021Article
- Parental Attitudes Toward Clinical Genomic Sequencing in Children With Critical Cardiac Disease.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2021Article
- Genetic literacy and psychological adaptation in adolescents with genetic diseasesRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2021Article
- Attitudes towards genetic testing and information: does parenthood shape the views?Journal of community genetics · 2020Article
- What do people think about genetics? A systematic review.Journal of community genetics · 2019Review
- Tell me once, tell me soon: parents' preferences for clinical genetics services for congenital heart disease.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Patient and provider perspectives on the development of personalized medicine: a mixed-methods approach.Journal of community genetics · 2018Article
- Genetic Knowledge Among Participants in the Coriell Personalized Medicine Collaborative.Journal of genetic counseling · 2016Article
- Measuring genetic knowledge: a brief survey instrument for adolescents and adults.Clinical genetics · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Clinical genetic testing for specific isolated congenital heart defects (CHD) is becoming standard of care in pediatric cardiology practice. Both genetic knowledge and attitudes toward genetic testing are associated with an increased utilization of genetic testing, but these factors have not been evaluated in parents of children with CHD. We mailed a survey to measure the demographics, genetic knowledge, and attitudes towards genetic testing of parents of children with CHD who previously consented to participate in a separate research study of the genetic etiology of left ventricular outflow tract malformations (LVOT). Of the 378 eligible families, 190 (50%) returned surveys with both parents completing surveys in 97 (51%) families, resulting in 287 participants. Genetic knowledge was assessed on an adapted measure on which the mean percent correct was 73.8%. Educational attainment and household income were directly and significantly associated with genetic knowledge (P < 0.001). Attitudes about the health effects of genetic testing were favorable with at least 57% agreeing that genetic testing would be used for managing health care and finding cures for disease. Conversely, a minority of participants found it likely that genetic testing would be used for insurance (up to 39.9%), employment (15.8%), or racial/social discrimination (up to 11.2%). Parents of younger children were less likely to endorse employment or racial/social discrimination. Genetic knowledge was not correlated with specific attitudes. Among parents of children with CHD, genetic knowledge was directly associated with household income and education, but additional research is necessary to determine what factors influence attitudes towards genetic testing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.