ArticleInternational dental journal2015
Role of human papilloma virus-16 in the pathogenesis of oral lichen planus--an immunohistochemical study.
Article in International dental journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- The correlation between human papillomavirus and oral lichen planus: A systematic review of the literature.Immunity, inflammation and disease · 2023Pooled it
- The Magnitude of the Association between Human Papillomavirus and Oral Lichen Planus: A Meta-Analysis.PloS one · 2016Pooled it
- Local and General Inflammatory Mediators Status in Patients with Oral Lichen Planus.Biomedicines · 2026Article
- Function of unconventional T cells in oral lichen planus revealed by single-cell RNA sequencing.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- Salivary Histamine Levels in Patients with Oral Lichen Planus Lesions.Medicina (Kaunas, Lithuania) · 2024Article
- Human Papillomavirus in Oral Lichen Planus: Is There an Association? A Meta-Analysis.Journal of clinical medicine · 2024Review
- Correlation between Oral Lichen Planus and Viral Infections Other Than HCV: A Systematic Review.Journal of clinical medicine · 2022Review
- Human papillomavirus in premalignant oral lesions: No evidence of association in a Spanish cohort.PloS one · 2019Article
- Possible roles of exosomal miRNAs in the pathogenesis of oral lichen planus.American journal of translational research · 2019Review
- Prevalence of human papillomavirus in oral lichen planus in an Iranian cohort.Journal of oral and maxillofacial pathology : JOMFPArticle
- Expression of human papillomavirus 16 and 18 DNA in oral lichen planus using polymerase chain reaction.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOral lichen planus (OLP) is a common chronic inflammatory immune-mediated disease with an aetiopathogenesis associated with cell-mediated immunological dysfunction. It is possible that oral mucosal viral infections, including human papilloma virus-16 (HPV-16) infection, may have a causative role in OLP pathogenesis.
aimTo assess the prevalence of HPV-16 in histopathologically diagnosed specimens of OLP and to evaluate whether any clinical features (such as the localisation of specimens) or the age or gender of patients, are correlated with the presence of this virus. MATERIALS AND
methodsThis study was conducted on 30 specimens with a histopathological diagnosis of OLP, using the immunohistochemical marker HPV-16. Thirty normal oral mucosa specimens were also included as controls. Brown nuclear staining was accepted as positive for the HPV-16 antibody. The results were analysed using Fisher's exact test. P values<0.05 were considered to be significant.
resultsSignificant correlation (P=0.0001) was observed between HPV-16 infection and samples with OLP. No statistical conclusions could be drawn regarding age, gender, localisation and HPV-16 positivity.
conclusionOur study showed that HPV-16 may play a role in the pathogenesis of OLP. Taking into account the oncogenic potential of HPV-16, patients with OLP should be screened for the presence of this virus.
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