ArticleJournal of the American Association for Laboratory Animal Science : JAALAS2014
Effect of Corncob bedding on feed conversion efficiency in a high-fat diet-induced prediabetic model in C57Bl/6J mice.
Article in Journal of the American Association for Laboratory Animal Science : JAALAS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Enhancing Rodent Welfare, Cost Savings, and Efficiency: Implementation and Review of Data-Driven Improvements.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Review
- Beyond Comfort: A Review of the Critical Role of Bedding Selection in Rodent Welfare, Microenvironment, and Research Reproducibility.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Review
- Guidelines for diet-induced models of cardiometabolic syndrome.American journal of physiology. Heart and circulatory physiology · 2025Review
- Breeding fat-tailed dunnarts (Sminthopsis crassicaudata) in captivity: Revised practices to minimize stress whilst maintaining considerations of wild biology.Developmental dynamics : an official publication of the American Association of Anatomists · 2025Article
- A Review of the Effects of Some Extrinsic Factors on Mice Used in Research.Comparative medicine · 2023Review
- Bedding as a variable affecting fasting blood glucose and vascular physiology in mice.American journal of physiology. Heart and circulatory physiology · 2023Article
- Chowing down: diet considerations in rodent models of metabolic disease.Life metabolism · 2023Article
- Effect of Bedding Substrates on Blood Glucose and Body Weight in Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2022Article
- Review
- Interactive effects of compounding multidimensional stressors on maternal and male and female rat offspring outcomes.Hormones and behavior · 2021Article
- Weight Gain, Glucose Tolerance, and the Gut Microbiome of Male C57BL/6J Mice Housed on Corncob or Paper Bedding and Fed Normal or High-Fat Diet.Journal of the American Association for Laboratory Animal Science : JAALAS · 2021Article
- Evaluation of Potential Sustainable Bedding Substrates Focusing on Preference, Behavior, and Stress Physiology in Rats-A Pilot Study.Animals : an open access journal from MDPI · 2021Article
- A high-protein diet containing inulin/oligofructose supports body weight gain associated with lower energy expenditure and carbohydrate oxidation, and alters faecal microbiota in C57BL/6 mice.Journal of nutritional science · 2021Article
- Cage bedding modifies metabolic and gut microbiota profiles in mouse studies applying dietary restriction.Scientific reports · 2020Article
- Comparative Effects of 1/4-inch and 1/8-inch Corncob Bedding on Cage Ammonia Levels, Behavior, and Respiratory Pathology of Male C57BL/6 and 129S1/Svlm Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Compressed Paper as an Alternative to Corn Cob Bedding in Mouse (Journal of the American Association for Laboratory Animal Science : JAALAS · 2020Article
- Immune Relevant and Immune Deficient Mice: Options and Opportunities in Translational Research.ILAR journal · 2018Review
- Considerations and guidelines for mouse metabolic phenotyping in diabetes research.Diabetologia · 2018Review
- Article
- The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets.Diabetologia · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Laboratory facilities use many varieties of contact bedding, including wood chips, paper products, and corncob, each with its own advantages and disadvantages. Corncob bedding, for example, is often used because of its high absorbency, ability to minimize detectable ammonia, and low cost. However, observations that mice eat the corncob lead to concerns that its use can interfere with dietary studies. We evaluated the effect of corncob bedding on feed conversion (change in body weight relative to the apparent number of kcal consumed over 7 d) in mice. Four groups of mice (6 to 12 per group) were housed in an individually ventilated caging system: (1) low-fat diet housed on recycled paper bedding, (2) low-fat diet housed on corncob bedding, (3) high-fat diet housed on recycled paper bedding, and (4) high-fat diet housed on corncob bedding. After 4 wk of the high-fat diet, feed conversion and percentage body weight change both were lower in corncob-bedded mice compared with paper-bedded mice. Low-fat-fed mice on corncob bedding versus paper bedding did not show statistically significant differences in feed conversion or change in percentage body weight. Average apparent daily feed consumption did not differ among the 4 groups. In conclusion, these data suggest that corncob bedding reduces the efficiency of feed conversion in mice fed a high-fat diet and that other bedding choices should be favored in these models.
Indexed as
Identifiers
25255066PMC4181685What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.