Evidence map›Paper›PMID 25254651›Full record

ArticleLab on a chip2014

Creating sub-50 nm nanofluidic junctions in a PDMS microchip via self-assembly process of colloidal silica beads for electrokinetic concentration of biomolecules.

A Syed, L Mangano, P Mao, J Han, Y-A Song

Abstract read
In one paragraph

Article in Lab on a chip, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Recent progress of microfluidic chips in immunoassay.Frontiers in bioengineering and biotechnology · 2022
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A SyedNew York University Abu Dhabi, Division of Engineering, PO Box 129188, Abu Dhabi, UAE. rafael.song@nyu.edu.
L Mangano
P Mao
J Han
Y-A Song

Funding

Continuous-flow, Ampholyte-free pI-based Sorting Peptides/proteins at Extreme pHR21EB008177 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HAN, JONGYOON · 2010 to 2011
$416k
NIBIB NIH HHS R21 EB008177NIBIB NIH HHS R21 EB008177-01A2
6 · The paper itself

Abstract

In this work we describe a novel and simple self-assembly process of colloidal silica beads to create a nanofluidic junction between two microchannels. The nanoporous membrane was used to induce ion concentration polarization inside the microchannel and this electrokinetic preconcentration system allowed rapid concentration of DNA samples by ~1700 times and of protein samples by ~100 times within 5 minutes.

Indexed as

ColloidsDimethylpolysiloxanesDNAEquipment DesignMicrofluidic Analytical TechniquesNanostructuresNylonsProteinsSilicon DioxideColloidsDimethylpolysiloxanesDNANylonspoly(dimethylsiloxane)-polyamide copolymerProteinsSilicon Dioxide

Identifiers

PMID25254651
PMCPMC4213239

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.