ArticleAnalytical chemistry2014
Metabolite content profiling of bottlenose dolphin exhaled breath.
Article in Analytical chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed.
- Reproductive Science Methods for Marine Mammals.Advances in experimental medicine and biology · 2026Review
- Origin of breath isoprene in humans is revealed via multi-omic investigations.Communications biology · 2023Article
- Using Blood Gas Analysis and Capnography to Determine Oxygenation Status in Bottlenose Dolphins (Toxics · 2023Article
- Climate change and cetacean health: impacts and future directions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Preservation of vapor samples on adsorbent alumina capillaries and implications for field sampling.Journal of chromatography. A · 2021Article
- Plasma metabolomic analysis in mature female common bottlenose dolphins: profiling the characteristics of metabolites after overnight fasting by comparison with data in beagle dogs.Scientific reports · 2018Article
- Quantifying hormones in exhaled breath for physiological assessment of large whales at sea.Scientific reports · 2018Article
- Power-efficient self-cleaning hydrophilic condenser surface for portable exhaled breath condensate (EBC) metabolomic sampling.Journal of breath research · 2018Article
- Analytical methodologies for broad metabolite coverage of exhaled breath condensate.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2017Article
- Human breath metabolomics using an optimized non-invasive exhaled breath condensate sampler.Journal of breath research · 2016Article
- Enhanced non-invasive respiratory sampling from bottlenose dolphins for breath metabolomics measurements.Journal of breath research · 2016Article
- Get the most out of blow hormones: validation of sampling materials, field storage and extraction techniques for whale respiratory vapour samples.Conservation physiology · 2016Article
- Dolphins and diabetes: applying one health for breakthrough discoveries.Frontiers in endocrinology · 2014Article
- PCA as a practical indicator of OPLS-DA model reliability.Current MetabolomicsArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Changing ocean health and the potential impact on marine mammal health are gaining global attention. Direct health assessments of wild marine mammals, however, is inherently difficult. Breath analysis metabolomics is a very attractive assessment tool due to its noninvasive nature, but it is analytically challenging. It has never been attempted in cetaceans for comprehensive metabolite profiling. We have developed a method to reproducibly sample breath from small cetaceans, specifically Atlantic bottlenose dolphins (Tursiops truncatus). We describe the analysis workflow to profile exhaled breath metabolites and provide here a first library of volatile and nonvolatile compounds in cetacean exhaled breath. The described analytical methodology enabled us to document baseline compounds in exhaled breath of healthy animals and to study changes in metabolic content of dolphin breath with regard to a variety of factors. The method of breath analysis may provide a very valuable tool in future wildlife conservation efforts as well as deepen our understanding of marine mammals biology and physiology.
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Registered trials
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