Observational studyPloS one2014
Neuroticism associated with cocaine-induced psychosis in cocaine-dependent patients: a cross-sectional observational study.
Observational study in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 23 citations in OpenAlex.
- Gender differences in ADHD and impulsivity among alcohol or alcohol- and cocaine-dependent patients.Frontiers in psychiatry · 2025Article
- Oral and fecal microbiota perturbance in cocaine users: Can rTMS-induced cocaine abstinence support eubiosis restoration?iScience · 2023Article
- Therapeutic Use and Chronic Abuse of CNS Stimulants and Anabolic Drugs.Current issues in molecular biology · 2022Review
- The Importance of a Multi-Disciplinary Approach to the Endometriotic Patients: The Relationship between Endometriosis and Psychic Vulnerability.Journal of clinical medicine · 2021Review
- Personality Traits and Psychotic Proneness Among Chronic Synthetic Cannabinoid Users.Frontiers in psychiatry · 2020Article
- Anxiety and Depression in Drug-Dependent Patients with Cluster C Personality Disorders.Frontiers in psychiatry · 2018Article
- Psychometric properties of the 7-item game addiction scale among french and German speaking adults.BMC psychiatry · 2016Article
- Transcriptomic and genetic studies identify NFAT5 as a candidate gene for cocaine dependence.Translational psychiatry · 2015Article
- Psychopathology in Substance Use Disorder Patients with and without Substance-Induced Psychosis.Journal of addiction · 2015Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCocaine consumption can induce transient psychotic symptoms, which has been correlated with more severe addiction and aggressive behavior. However, little is known about the nature of the relationship between personality traits and psychotic symptoms in cocaine-dependent patients. This study examined the relationship between neuroticism and cocaine-induced psychosis.
methodsA total of 231 cocaine-dependent patients seeking treatment were recruited to the study. Personality was evaluated by the Zuckerman-Kuhlman Personality Questionnaire. Cocaine-induced psychosis questionnaire, SCID-I, and SCID-II were used to evaluate comorbidity and clinical characteristics. Data analysis was performed in three steps: descriptive, bivariate, and multivariate analyses.
resultsCocaine-induced psychosis was reported in 65.4% of the patients and some personality disorder in 46.8%. Two personality dimensions (Neuroticism-Anxiety and Aggression-Hostility) presented a significant effect on the risk of experiencing psychotic symptoms (t(229) = 2.69, p = 0.008; t(229) = 2.06, p = 0.004), and patients with psychotic symptoms showed higher scores in both variables. On the multivariate analysis, only Neuroticism remained as a significant personality factor independently associated with psychotic symptoms (Wald = 7.44, p<0.05, OR = 1.08, CI 95% 1.02-1.16) after controlling for age, gender and number of consumption substances.
conclusionsAn association between high neuroticism scores and presence of psychotic symptoms induced by cocaine has been found, independently of other consumption variables. Personality dimensions should be evaluated in cocaine-dependent patients in order to detect high scores of neuroticism and warn patients about the risk of developing cocaine-induced psychotic symptoms.
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