Evidence map›Paper›PMID 25254201›Full record

ArticleToxics2014

Short-term traffic related exposures and biomarkers of nitro-PAH exposure and oxidative DNA damage.

Andreas M Neophytou, Jaime E Hart, Yan Chang, Junfeng Jim Zhang, Thomas J Smith, Eric Garshick, Francine Laden

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Effects of ambient PMToxicology research · 2017
    Article
  7. Article
  8. Air pollution and allergic diseases.Current opinion in pediatrics · 2015
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Andreas M NeophytouDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA ; Division of Environmental Health Sciences, UC Berkeley School of Public Health, Berkeley, CA, USA.
Jaime E HartDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA ; Channing Division of Network Medicine, Brigham and Women's and Hospital Harvard Medical School, Boston, MA, USA.
Yan ChangDepartment of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA.
Junfeng Jim ZhangNicholas School of the Environment, & Duke Global Health Institute, Duke University Durham, NC, USA.
Thomas J SmithDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA.
Eric GarshickPulmonary and Critical Care Medicine Section, VA Boston Healthcare System, Boston, MA, USA ; Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA.
Francine LadenDepartment of Environmental Health, Harvard School of Public Health, Boston, MA, USA ; Channing Division of Network Medicine, Brigham and Women's and Hospital Harvard Medical School, Boston, MA, USA.
Brigham and Women's Hospital · USBerkeley Public Health Division · USDuke University · USUniversity of Southern California · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
BIOMARKERS OF EXPOSURE AND EFFECT IN A TRAFFIC EXPOSED POPULATIONR01ES016284 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI LADEN, FRANCINE · 2008 to 2011
$2.8M
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES016284
6 · The paper itself

Abstract

Exposure to vehicle exhaust has been associated with cardiac and respiratory disease, lung cancer, and greater overall mortality. We investigated whether amino- polycyclic aromatic hydrocarbon (amino-PAH) metabolites of nitro-PAHs could be used as biomarkers of these exposures. Pre- and post-shift urine samples were collected at the beginning and end of a work week from 82 male U.S trucking industry workers. We used repeated-measures analysis to examine associations of total 1- and 2-aminonaphthalene (1 & 2-AN) and 1-aminopyrene (1-AP) urinary concentrations with microenvironment exposures to particulate matter (PM

Indexed as

biomarkersnitro-PAHsoxidative stresstraffic emissions

Identifiers

PMID25254201
PMCPMC4169896
OpenAlexW2016986933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.