Evidence map›Paper›PMID 25254052›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2014

Protective effect of huoxiang zhengqi oral liquid on intestinal mucosal mechanical barrier of rats with postinfectious irritable bowel syndrome induced by acetic Acid.

Yao Liu, Wei Liu, Qiu-Xian Peng, Jiang-Li Peng, Lin-Zhong Yu, Jian-Lan Hu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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  13. Nitrate Is Crucial for the Proliferation of GutFrontiers in microbiology · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yao LiuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China ; New Drug Research and Development Center, Guangdong Institute of Traditional Chinese Medicine, Guangzhou 510520, China.
Wei LiuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Qiu-Xian PengSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China ; Department of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong.
Jiang-Li PengCollege of Pharmacy, Hunan University of Traditional Chinese Medicine, Changsha 410028, China.
Lin-Zhong YuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Jian-Lan HuSchool of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China.
Southern Medical University · CNHong Kong Baptist University · HKHunan University of Traditional Chinese Medicine · CNTraditional Chinese Medicine Bureau of Guangdong Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a rat model with acetic acid-induced PI-IBS was used to study the role of HXZQ oral liquid in repairing the colonic epithelial barrier and reducing intestinal permeability. Pathomorphism of colonic tissue, epithelial ultrastructure, DAO activity in serum, and the protein expression of ZO-1 and occludin were examined to investigate protective effect mechanisms of HXZQ on intestinal mucosa barrier and then present experimental support for its use for prevention and cure of PI-IBS.

Identifiers

PMID25254052
PMCPMC4164314
OpenAlexW2055923895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.