Evidence map›Paper›PMID 25254006›Full record

ArticlePostepy dermatologii i alergologii2014

Evaluation of clinico-epidemiological and histopathological features of pityriasis rosea.

Gaye Devrim Ozyürek, Sevil Alan, Erol Cenesizoğlu

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Interventions for pityriasis rosea.The Cochrane database of systematic reviews · 2019
    Pooled it
  2. Review
  3. Article
  4. [Paraviral exanthems].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2017
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Gaye Devrim OzyürekDepartment of Dermatology and Venereology, Private Modern World Hospital, Kayseri, Turkey. Head of Department: Gaye Devrim Özyürek.
Sevil AlanDepartment of Dermatology and Venereology, Faculty of Medicine, Akdeniz University, Antalya, Turkey. Head of Department: Erkan Alpsoy.
Erol CenesizoğluDepartment of Dermatology and Venereology, Adana Numune Education and Research Hospital, Adana, Turkey. Head of Department: Erol Çenesizoğlu.
Akdeniz University · TRErciyes University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPityriasis rosea is a sudden-onset and self limiting disease with specific skin rash. The exact etiology is still not clear.

aimTo determine epidemiological, etiological, clinical and histopathological features in pityriasis rosea (PR). MATERIAL AND

methodsFifty two patients (older than 18 years) with PR were included in this study. Patients were examined for epidemiological and etiological features. Biopsy specimens obtained from secondary eruptions were histopathologically evaluated with hematoxylin-eosine and immunohistochemically evaluated with CD3 and CD20 monoclonal antibodies.

resultsAge range of patients was 18-53, mean age was 29.3 ±9.5 and women-to-men ratio was 1.08/1. Thirty-nine (75%) patients had a history of wearing new clothes, 27 (51.9%) patients had a history of recent respiratory tract infection, 15 (28.8%) patients had a history of recent gastrointestinal infection. Eczematous changes were detected in biopsy materials by histopathological evaluation, and cellular infiltrate was positively stained with pan T-cell marker CD3 and negatively stained with B lymphocyte marker CD20 in all biopsy materials in immunohistochemical examination.

conclusionsIn our study, frequency of pre-disease infection and prodromal symptoms history were determined to be higher than the results of similar studies in the literature. These higher results suggest that PR may be delayed-type hypersensitivity to an infectious factor. However, positive staining of all biopsy materials with pan T lymphocyte marker CD3 supports the association with cellular immunity. We believe that more extensive studies are needed on this issue.

Indexed as

epidemiologyetiologyhistopathologypityriasis rosea

Identifiers

PMID25254006
PMCPMC4171665
OpenAlexW2013160246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.