Evidence map›Paper›PMID 25254005›Full record

ArticlePostepy dermatologii i alergologii2014

Assessment of the usefulness of dihydrotestosterone in the diagnostics of patients with androgenetic alopecia.

Izabela Urysiak-Czubatka, Małgorzata L Kmieć, Grażyna Broniarczyk-Dyła

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Recent advances in inflammation & allergy drug discovery · 2025
    Article
  8. Review
  9. Article
  10. Nutrients · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Iranian journal of pharmaceutical research : IJPR · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. 17Biomedicines · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Izabela Urysiak-CzubatkaDepartment of General Dermatology, Esthetic and Dermatosurgery, Medical University of Lodz, Poland. Head of Department: Prof. Grażyna Broniarczyk-Dyła MD, PhD.
Małgorzata L KmiećDepartment of General Dermatology, Esthetic and Dermatosurgery, Medical University of Lodz, Poland. Head of Department: Prof. Grażyna Broniarczyk-Dyła MD, PhD.
Grażyna Broniarczyk-DyłaDepartment of General Dermatology, Esthetic and Dermatosurgery, Medical University of Lodz, Poland. Head of Department: Prof. Grażyna Broniarczyk-Dyła MD, PhD.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAndrogenetic alopecia (AGA) is the most common form of hair loss. Clinically observed hair loss is due to the continuous miniaturization of affected hair follicles. Genetic factors and androgenic factors especially dihydrotestosterone (DHT), which is a testosterone tissue metabolite, play major roles in the pathogenesis of AGA. However, expert opinions about the usefulness of DHT in the diagnosis of this type of alopecia are divided.

aimTo evaluate the usefulness of DHT level in patients with androgenetic alopecia compared with the control group. MATERIAL AND

methodsThe study comprised 49 subjects: 19 women and 9 men with androgenetic alopecia. The control group consisted of 17 healthy women and 4 men without hair loss.

resultsIncreased serum concentrations of DHT were observed in patients with androgenetic alopecia (17 women, 5 men), but also in the control group. The differences in mean values of DHT were not significant according to the types of alopecia and the control group. Increased serum concentrations of DHT were not correlated with the advance of alopecia.

conclusionsDihydrotestosterone is the most influential androgen and seems to play a very important role in the pathogenesis of androgenetic alopecia. Based on the results of our study and others, the most important factors would appear to be the genetically-determined sensitivity of the follicles to DHT and their different reactions to androgen concentration.

Indexed as

androgenetic alopeciadiagnosticdihydrotestosterone

Identifiers

PMID25254005
PMCPMC4171668
OpenAlexW2093117337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.