SynthesisWorld journal of gastroenterology2014
Occupational exposures and colorectal cancers: a quantitative overview of epidemiological evidence.
Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review.Ecotoxicology and environmental safety · 2021Pooled it
- Cancer and occupational exposure to pesticides: an umbrella review.International archives of occupational and environmental health · 2021Pooled it
- Exploring Risk Factors and Sex Differences in Colorectal Cancer: Insights from Current Evidence.Cells · 2026Review
- Review
- Article
- Detection of Unlabeled Polystyrene Micro- and Nanoplastics in Mammalian Tissue by Optical Photothermal Infrared Spectroscopy.Analytical chemistry · 2025Article
- Father's occupation and colorectal cancer in his adult offspring.Journal of the National Cancer Institute · 2025Article
- Social-Environmental Burden Is Associated with Increased Colorectal Cancer Mortality in Metropolitan Detroit.Cancer research communications · 2025Article
- Epidemiology of colorectal cancer: A review with special emphasis on India.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025Review
- Microplastics in aquatic systems: A comprehensive review of its distribution, environmental interactions, and health risks.Environmental science and pollution research international · 2025Review
- Impact of micro-nano plastics in daily life on human health: toxicological evaluation from the perspective of normal tissue cells and organoids.Toxicology research · 2024Review
- Microplastics in the Human Body: Exposure, Detection, and Risk of Carcinogenesis: A State-of-the-Art Review.Cancers · 2024Review
- Lifetime employment trajectories and cancer.Scientific reports · 2024Article
- The OCCHLTH Mnemonic-Construction and Content of a Tool for Increasing Awareness of Occupational Illness and Injury.Journal of occupational and environmental medicine · 2024Review
- Nanoplastics Penetrate Human Bronchial Smooth Muscle and Small Airway Epithelial Cells and Affect Mitochondrial Metabolism.International journal of molecular sciences · 2024Article
- Lifetime Employment Trajectories and Cancer: A Population-Based Cohort Study.Research square · 2024Article
- Changing epidemiology of colorectal cancer - birth cohort effects and emerging risk factors.Nature reviews. Gastroenterology & hepatology · 2024Review
- Article
- Colorectal Cancer: 35 Cases in Asbestos-Exposed Workers.Healthcare (Basel, Switzerland) · 2023Article
- Association of occupational heat exposure and colorectal cancer in the MCC-Spain study.Scandinavian journal of work, environment & health · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A traditional belief widespread across the biomedical community was that dietary habits and genetic predisposition were the basic factors causing colorectal cancer. In more recent times, however, a growing evidence has shown that other determinants can be very important in increasing (or reducing) incidence of this malignancy. The hypothesis that environmental and occupational risk factors are associated with colorectal cancer is gaining ground, and high risks of colorectal cancer have been reported among workers in some industrial branches. The aim of this study was to investigate the epidemiologic relationship between colorectal cancer and occupational exposures to several industrial activities, by means of a scientific literature review and meta-analysis. This work pointed out increased risks of colorectal cancer for labourers occupied in industries with a wide use of chemical compounds, such as leather (RR = 1.70, 95%CI: 1.24-2.34), basic metals (RR = 1.32, 95%CI: 1.07-1.65), plastic and rubber manufacturing (RR = 1.30, 95%CI: 0.98-1.71 and RR = 1.27, 95%CI: 0.92-1.76, respectively), besides workers in the sector of repair and installation of machinery exposed to asbestos (RR = 1.40, 95%CI: 1.07-1.84). Based on our results, the estimated crude excess risk fraction attributable to occupational exposure ranged from about 11% to about 15%. However, homogeneous pattern of association between colorectal cancer and industrial branches did not emerge from this review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.