Evidence map›Paper›PMID 25253918›Full record

ArticleEurophysics letters2014

Multicanonical Molecular Dynamics Simulations of the N-terminal Domain of Protein L9.

Fatih Yaşar, Ping Jiang, Ulrich H E Hansmann

Abstract read
In one paragraph

Article in Europhysics letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fatih YaşarDepartment of Physics Engineering, Hacettepe University, Ankara, 06800, TURKEY.
Ping JiangDepartment of Chemistry & Biochemistry, University of Oklahoma, Norman, OK 73019-5251, USA.
Ulrich H E HansmannDepartment of Chemistry & Biochemistry, University of Oklahoma, Norman, OK 73019-5251, USA.

Funding

Folding, Mis-Folding and Aggregation of Small ProteinsR01GM062838 · NIGMS · UNIVERSITY OF OKLAHOMA · PI HANSMANN, ULRICH H.E. · 2003 to 2012
$1.4M
NIGMS NIH HHS R01 GM062838
6 · The paper itself

Abstract

We describe multicanonical molecular dynamic simulations of the N-terminal domain of the protein L9. Analyzing free energy landscapes and thermal ordering, we propose a possible folding mechanism for the protein. By comparing our results with that of molecular dynamics runs of the protein at constant temperature, we find that multicanonical molecular dynamics leads to orders of magnitude higher sampling of folding transitions.

Identifiers

PMID25253918
PMCPMC4169893

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.