Evidence map›Paper›PMID 25253744›Full record

ArticleNeurology2014

Null mutation in SCN9A in which noxious stimuli can be detected in the absence of pain.

Juan D Ramirez, Abdella M Habib, James J Cox, Andreas C Themistocleous, Stephen B McMahon, John N Wood, David L H Bennett

Registry-linked trialAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02696746 (Painful Channelopathies Study), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02696746 unknown statusnot on this map

Painful Channelopathies Study

TypeobservationalSponsorKing's College LondonRan2012Enrolled100ConditionsErythromelalgia, Pain Insensitivity, Congenital, Hereditary Sensory and Autonomic Neuropathies, Chronic PainArmsObservation
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juan D RamirezFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK.
Abdella M HabibFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK.
James J CoxFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK.
Andreas C ThemistocleousFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK.
Stephen B McMahonFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK.
John N WoodFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK.
David L H BennettFrom the University of Oxford (J.D.R., A.C.T., D.L.H.B.); Wolfson Institute for Biomedical Research (A.M.H., J.J.C., J.N.W.), University College London; and Wolfson CARD (S.B.M.), King's College London, UK. david.bennett@ndcn.ox.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/F000227/1Medical Research Council G0901905Medical Research Council G1100340Medical Research Council G120/818Wellcome Trust 083259Wellcome Trust 095698Wellcome Trust 101054Wellcome Trust 102645
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultGenetic TestingHumansMaleMutationNAV1.7 Voltage-Gated Sodium ChannelPainNAV1.7 Voltage-Gated Sodium ChannelSCN9A protein, human

Identifiers

PMID25253744
PMCPMC4222855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.