ArticleBMC genomics2014
Plant protein peptidase inhibitors: an evolutionary overview based on comparative genomics.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- A Volatile Cue From a Specialist Herbivore Primes Gene Expression Against Biotic Stress in Tall Goldenrod (Solidago altissima L.).Plant, cell & environment · 2026Article
- Kazal-type serine protease inhibitors from Arabidopsis thaliana and Toxoplasma gondii exhibit antimicrobial activity against plant pathogens.Scientific reports · 2026Article
- Article
- A Novel Kunitz Trypsin Inhibitor fromMolecules (Basel, Switzerland) · 2024Article
- Shallow water seeding cultivation enhances cold tolerance in tobacco seedlings.BMC plant biology · 2024Article
- Identification of bromelain subfamily proteases encoded in the pineapple genome.Scientific reports · 2023Article
- Identification of Proteases and Protease Inhibitors in Seeds of the Recalcitrant Forest Tree SpeciesFrontiers in plant science · 2022Article
- Genome-Wide Screening of Broad-Spectrum Resistance to Leaf Rust (Frontiers in plant science · 2022Article
- Aethionema arabicum genome annotation using PacBio full-length transcripts provides a valuable resource for seed dormancy and Brassicaceae evolution research.The Plant journal : for cell and molecular biology · 2021Article
- Modeling of the Potential Geographical Distribution of ThreeFrontiers in plant science · 2021Article
- Developmental Analysis of the GATA FactorFrontiers in plant science · 2021Article
- Novel Monomeric Fungal Subtilisin Inhibitor from a Plant-Pathogenic Fungus, Choanephora cucurbitarum: Isolation and Molecular Characterization.Applied and environmental microbiology · 2020Article
- Genome Wide Identification and Comparative Analysis of the Serpin Gene Family in Brachypodium and Barley.Plants (Basel, Switzerland) · 2020Article
- Article
- Plant Serine Protease Inhibitors: Biotechnology Application in Agriculture and Molecular Farming.International journal of molecular sciences · 2019Review
- Messages From the Past: New Insights in Plant Lectin Evolution.Frontiers in plant science · 2019Article
- Arabidopsis Kunitz Trypsin Inhibitors in Defense Against Spider Mites.Frontiers in plant science · 2018Article
- Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions.International journal of biological macromolecules · 2017Review
- A novel subtilase inhibitor in plants shows structural and functional similarities to protease propeptides.The Journal of biological chemistry · 2017Article
- An Alternative Nested Reading Frame May Participate in the Stress-Dependent Expression of a Plant Gene.Frontiers in plant science · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeptidases are key proteins involved in essential plant physiological processes. Although protein peptidase inhibitors are essential molecules that modulate peptidase activity, their global presence in different plant species remains still unknown. Comparative genomic analyses are powerful tools to get advanced knowledge into the presence and evolution of both, peptidases and their inhibitors across the Viridiplantae kingdom.
resultsA genomic comparative analysis of peptidase inhibitors and several groups of peptidases in representative species of different plant taxonomic groups has been performed. The results point out: i) clade-specific presence is common to many families of peptidase inhibitors, being some families present in most land plants; ii) variability is a widespread feature for peptidase inhibitory families, with abundant species-specific (or clade-specific) gene family proliferations; iii) peptidases are more conserved in different plant clades, being C1A papain and S8 subtilisin families present in all species analyzed; and iv) a moderate correlation among peptidases and their inhibitors suggests that inhibitors proliferated to control both endogenous and exogenous peptidases.
conclusionsComparative genomics has provided valuable insights on plant peptidase inhibitor families and could explain the evolutionary reasons that lead to the current variable repertoire of peptidase inhibitors in specific plant clades.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.