Evidence map›Paper›PMID 25253394›Full record

ArticleBMC cancer2014

Physical activity and renal cell carcinoma among black and white Americans: a case-control study.

Qian Xiao, Linda Liao, Charles E Matthews, Wong-Ho Chow, Faith Davis, Kendra Schwartz, Mark Purdue, Jonathan N Hofmann, Joanne Colt

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Qian XiaoDivision of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. qian.xiao@nih.gov.
Linda Liao
Charles E Matthews
Wong-Ho Chow
Faith Davis
Kendra Schwartz
Mark Purdue
Jonathan N Hofmann
Joanne Colt
National Institutes of Health · USNational Cancer Institute · USThe Barbara Ann Karmanos Cancer Institute · USThe University of Texas MD Anderson Cancer Center · USUniversity of Alberta · CA

Funding

Therapeutic &Diagnostic Factors Related to Cancer RisKZ01CP010128 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI BRINTON, LOUISE · 1996 to 2008
$146k
Intramural NIH HHS Z01 CP010128NCI NIH HHS N02 CP011004NCI NIH HHS N02 CP011161NCI NIH HHS N02-CP-10128
6 · The paper itself

Abstract

backgroundRenal cell carcinoma (RCC) has a higher incidence in blacks than in whites. Physical activity may influence the risk of renal cell cancer, but the evidence is inconsistent. No previous study has investigated this relationship in the black population.

methodsWe examined the association between self-reported physical activity at different ages and risk of RCC in a population based case-control study of 1217 cases (361 black, 856 white) and 1235 controls (523 black, 712 white) frequency-matched on age, race, and gender. Multivariate-adjusted odds ratios (OR) and 95% confidence intervals (CI) were estimated using unconditional logistic regression.

resultsAmong whites, increased risks of RCC were observed among participants reporting low levels of transportation-related activity in their 20's (OR <1 hr/wk vs >7 hr/wk (95% CI): 1.42 (1.10, 1.83)) and leisure time activity in their 50's (OR <1 hr/wk vs >7 hr/wk (95% CI): 1.49 (1.00, 2.20)). We found no association between physical activity and RCC risk among blacks.

conclusionOur results suggest that physical activity may be inversely associated with RCC risk in whites, but there was no evidence of such an association in blacks. As this is the first study evaluating the effect of physical activity on RCC risk among blacks, further investigations are needed to clarify the relationship in this population.

Indexed as

Black or African AmericanMotor ActivityWhite PeopleAdultAgedAged, 80 and overAge FactorsCarcinoma, Renal CellCase-Control StudiesFemaleHumansKidney NeoplasmsMaleMiddle AgedPopulation SurveillanceRisk Factors

Identifiers

PMID25253394
PMCPMC4181698
OpenAlexW2091658206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.