ArticleMethods in molecular biology (Clifton, N.J.)2015
Examining galectin binding specificity using glycan microarrays.
Article in Methods in molecular biology (Clifton, N.J.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- A Zebrafish Galectin-1 Isoform Is Expressed in Skin and Gills and Binds to Bacteria, Bacterial Adhesin Receptors, and Epidermal Mucus Glycans.International journal of molecular sciences · 2026Article
- Glycomimetics for the inhibition and modulation of lectins.Chemical Society reviews · 2023Review
- Whole microbe arrays accurately predict interactions and overall antimicrobial activity of galectin-8 toward distinct strains of Streptococcus pneumoniae.Scientific reports · 2023Article
- Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group-like antigens.The Journal of biological chemistry · 2022Article
- Evaluation of Galectin Binding by Surface Plasmon Resonance.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Purification of Recombinant Galectins from Different Species Using Distinct Affinity Chromatography Methods.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Galectins: An Ancient Family of Carbohydrate Binding Proteins with Modern Functions.Methods in molecular biology (Clifton, N.J.) · 2022Review
- IntroducingMethods in molecular biology (Clifton, N.J.) · 2022Article
- An Automated Approach to Assess Relative Galectin-Glycan Affinity Following Glycan Microarray Analysis.Frontiers in molecular biosciences · 2022Article
- Cephalosporium curvulum lectin causes mycotic keratitis by initiating infection through MyD88 dependent cellular proliferation and apoptosis in human corneal epithelial cells.Glycoconjugate journal · 2021Article
- Full-Length Galectin-3 Is Required for High Affinity Microbial Interactions and Antimicrobial Activity.Frontiers in microbiology · 2021Article
- Mammalian lectin arrays for screening host-microbe interactions.The Journal of biological chemistry · 2020Article
- Brugia malayi galectin 2 is a tandem-repeat type galectin capable of binding mammalian polysaccharides.Molecular and biochemical parasitology · 2020Article
- Long-term survival of pig-to-rhesus macaque renal xenografts is dependent on CD4 T cell depletion.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Article
- The Structural Biology of Galectin-Ligand Recognition: Current Advances in Modeling Tools, Protein Engineering, and Inhibitor Design.Frontiers in chemistry · 2019Review
- Protein glycosylation in cancer.Annual review of pathology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Glycan binding proteins (GBPs) possess the unique ability to regulate a wide variety of biological processes through interactions with highly modifiable cell surface glycans. While many studies demonstrate the impact of glycan modification on GBP recognition and activity, the relative contribution of subtle changes in glycan structure on GBP binding can be difficult to define. To overcome limitations in the analysis of GBP-glycan interactions, recent studies utilized glycan microarray platforms containing hundreds of structurally defined glycans. These studies not only provided important information regarding GBP-glycan interactions, but have also resulted in significant insight into the binding specificity and biological activity of the galectin family. We will describe the methods used when employing glycan microarray platforms to examine galectin-glycan binding specificity and function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.