Evidence map›Paper›PMID 25252972›Full record

ArticleNature2014

Cancer: The origin of human retinoblastoma.

Rod Bremner, Julien Sage

Abstract readComment
In one paragraph

Article in Nature, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Biomarkers in retinoblastoma.International journal of ophthalmology · 2020
    Review
  12. Article
  13. Developmental stage-specific proliferation and retinoblastoma genesis in RB-deficient human but not mouse cone precursors.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  14. Article
  15. Article
  16. Review
  17. MiR-145 suppressed human retinoblastoma cell proliferation and invasion by targeting ADAM19.International journal of clinical and experimental pathology · 2015
    Article
  18. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Rod BremnerMount Sinai Hospital, Lunenfeld Tanenbaum Research Institute, Toronto, Ontario M5G 1X5, Canada.
Julien SageDepartments of Pediatrics and Genetics, Stanford University, Stanford, California 94305, USA.

Funding

The RB pathway in liver cancerR01CA114102 · NCI · STANFORD UNIVERSITY · PI SAGE, JULIEN · 2006 to 2016
$2.9M
NCI NIH HHS R01 CA114102
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansRetinal Cone Photoreceptor CellsRetinoblastomaRetinoblastoma ProteinRetinoblastoma Protein

Identifiers

PMID25252972
PMCPMC5438154

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.