ArticleBMC public health2014
The Wuhan-Zhuhai (WHZH) cohort study of environmental air particulate matter and the pathogenesis of cardiopulmonary diseases: study design, methods and baseline characteristics of the cohort.
Article in BMC public health, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Gannan rare earth elements cohort: study design, methods, and baseline characteristics of the cohort.BMC public health · 2025Article
- Styrene and ethylbenzene exposure and type 2 diabetes mellitus: A longitudinal gene-environment interaction study.Eco-Environment & Health · 2024Article
- Baseline data and associations between urinary biomarkers of polycyclic aromatic hydrocarbons, blood pressure, hemogram, and lifestyle among wildland firefighters.Frontiers in public health · 2024Article
- Effects of exposure to fine particulate matter on the decline of lung function in rural areas in northwestern China.Environmental science and pollution research international · 2022Article
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- Sources of 24-h personal exposure to PMEnvironmental science and pollution research international · 2021Article
- Profile of copper-associated DNA methylation and its association with incident acute coronary syndrome.Clinical epigenetics · 2021Article
- Oxidative damage mediates the association between polycyclic aromatic hydrocarbon exposure and lung function.Environmental health : a global access science source · 2020Article
- Associations of Gain in Weight-Related Anthropometric Indices with a Marker of Lipid Peroxidation: A Cohort Study Among Urban Adults in China.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Systemic Inflammation Mediates the Associations Between Abdominal Obesity Indices and Lung Function Decline in a Chinese General Population.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Association of lung function with cardiovascular risk: a cohort study.Respiratory research · 2018Article
- Exposure to Polycyclic Aromatic Hydrocarbons and Accelerated DNA Methylation Aging.Environmental health perspectives · 2018Article
- Air pollution, UV irradiation and skin carcinogenesis: what we know, where we stand and what is likely to happen in the future?Postepy dermatologii i alergologii · 2017Review
- Aging with higher fractional exhaled nitric oxide levels are associated with increased urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine concentrations in elder females.Environmental science and pollution research international · 2016Article
- Short-term Effects of Outdoor Air Pollution on Lung Function among Female Non-smokers in China.Scientific reports · 2016Article
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Authors and funding
20 authors.
Funding
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Abstract
backgroundParticulate air pollution has been recognized to be associated with a wide range of adverse health effects, including increased mortality, morbidity, exacerbation of respiratory conditions. However, earlier physiological or pathological changes or long-term bodies' reaction to air pollutants have not been studied in depth in China. The Wuhan-Zhuhai (WHZH) cohort study is designed to investigate the association between air pollutants exposure and physiological or pathological reactions on respiratory and cardiovascular system. METHODS/
designThe cohort is a community-based prospective study that includes 4812 individuals aged 18-80 years. The collections of data were conducted from April to May 2011 in Wuhan city and in May 2012 in Zhuhai city. At baseline, data on demographic and socioeconomic information, occupational history, family disease history, lifestyle, cooking mode, daily travel mode, physical activity and living condition have been collected by questionnaires. Participants underwent an extensive physical examination, including anthropometry, spirometry, electrocardiography, and measurements of blood pressure, heart rate, exhaled nitric oxide and carbon monoxide. Potential conditions in the lung, heart, liver, spleen, and skin were synchronously performed. In addition, samples of morning urine, fasting blood serum and plasma were collected during physical health examination. DNA were extracted and were stored at -80°C. Environment concentrations of particulate matter and chemicals were determined for 15 days in each of four seasons. Participants are followed for physiological or pathological changes or incidence of cardiopulmonary diseases every 3 years. DISCUSSION: The results obtained in WHZH cohort study may increase a better understanding of the relationship between particulate air pollution and its components and possible health damages. And the potential mechanisms underlying the development of cardiopulmonary diseases has implications for the development of prevention and treatment strategies.
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