ArticleNeuroradiology2014
Low dose CT perfusion in acute ischemic stroke.
Article in Neuroradiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Letter to the Editor: Cerebral CT perfusion dose: diagnostic reference levels should stimulate, not replace, optimization.Insights into imaging · 2026Article
- Real-world data on the impact of dose reduction measures on radiation exposure in CT perfusion of the brain.European journal of radiology open · 2026Article
- Effectiveness of low-tube current for reducing radiation dose in cerebral computed tomography perfusion.Archives of medical science : AMS · 2026Article
- Standardizing the estimation of ischemic regions can harmonize CT perfusion stroke imaging.European radiology · 2024Article
- Ultra-low-dose multiphase CT angiography derived from CT perfusion data in patients with middle cerebral artery stenosis.Neuroradiology · 2020Article
- Contrast-Medium Anisotropy-Aware Tensor Total Variation Model for Robust Cerebral Perfusion CT Reconstruction with Low-Dose Scans.IEEE transactions on computational imaging · 2020Article
- Focal Hypoperfusion in Acute Ischemic Stroke Perfusion CT: Clinical and Radiologic Predictors and Accuracy for Infarct Prediction.AJNR. American journal of neuroradiology · 2019Article
- Article
- TENDER: Tensor non-local deconvolution enabled radiation reduction in CT perfusion.Neurocomputing · 2017Article
- Iterative Reconstruction Improves Both Objective and Subjective Image Quality in Acute Stroke CTP.PloS one · 2016Article
- Temporal changes in blood-brain barrier permeability and cerebral perfusion in lacunar/subcortical ischemic stroke.BMC neurology · 2015Article
- Early CT perfusion changes and blood-brain barrier permeability after aneurysmal subarachnoid hemorrhage.Neuroradiology · 2015Article
- Multimodal CT provides improved performance for lacunar infarct detection.AJNR. American journal of neuroradiology · 2015Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe purpose of this investigation is to determine if CT perfusion (CTP) measurements at low doses (LD = 20 or 50 mAs) are similar to those obtained at regular doses (RD = 100 mAs), with and without the addition of adaptive statistical iterative reconstruction (ASIR).
methodsA single-center, prospective study was performed in patients with acute ischemic stroke (n = 37; 54% male; age = 74 ± 15 years). Two CTP scans were performed on each subject: one at 100 mAs (RD) and one at either 50 or 20 mAs (LD). CTP parameters were compared between the RD and LD scans in regions of ischemia, infarction, and normal tissue. Differences were determined using a within-subjects ANOVA (p < 0.05) followed by a paired t test post hoc analysis (p < 0.01).
resultsAt 50 mAs, there was no significant difference between cerebral blood flow (CBF), cerebral blood volume (CBV), or time to maximum enhancement (Tmax) values for the RD and LD scans in the ischemic, infarcted, or normal contralateral regions (p < 0.05). At 20 mAs, there were significant differences between the RD and LD scans for all parameters in the ischemic and normal tissue regions (p > 0.05).
conclusionCTP-derived CBF and CBV are not different at 50 mAs compared to 100 mAs, even without the addition of ASIR. Current CTP protocols can be modified to reduce the effective dose by 50 % without altering CTP measurements.
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