Evidence map›Paper›PMID 25252295›Full record

ArticleAnatolian journal of cardiology2015

Left atrial dyssynchrony time measured by tissue Doppler imaging to predict atrial fibrillation recurrences after pulmonary vein isolation.

Ahmed Salah, Hui Yang, Liang Tang, Xuping Li, Qiming Liu, Shenghua Zhou

Abstract readEvaluation Study
In one paragraph

Article in Anatolian journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ahmed SalahDepartment of Cardiology, Second Xiangya Hospital Central South University; Changsha-China. zhougqin@21cn.com.
Hui Yang
Liang Tang
Xuping Li
Qiming Liu
Shenghua Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this study we assess the value of left atrial dyssynchrony time measured by tissue Doppler imaging (TDI) to predict recurrences after pulmonary vein isolation (PVI) in patients with paroxysmal and persistent atrial fibrillation (AF).

methodsOne hundred sixty patients (57 ± 7.5 years, 122 males) with symptomatic drug-refractory paroxysmal and persistent AF, undergoing PVI were enrolled in our study. PA peak time by tissue Doppler imaging (PApeak-TDI) is defined as the time measured from the start of P wave in lead II to the peak of A wave on the tissue Doppler tracing. Left atrial dyssynchrony was measured by subtracting the PApeak-TDI time measured at the mid-inter atrial septum from the PA peak-TDI time measured at the left atrial midlateral free wall, (LA dyssynchrony = PApeak TDI lateral-PApeak TDI septal).

resultsDuring a mean follow-up of 12 ± 3 months, recurrences occurred in 50 out of 160 patients. Patients with recurrence of atrial fibrillation had larger left atrial dyssynchrony time (26.5 ± 2.4 ms vs. 23.5 ± 2.3 ms, p < 0.001). Left atrial dyssynchrony time of 25 ms has the best combined sensitivity and specificity (74% and 63% respectively) along with positive predictive value 53% and negative predictive value 85.5%. LA dyssynchrony time ≥ 25 ms was found to discriminate patients prone to AF recurrences over time. Multivariate regression analysis showed that left atrial dyssynchrony time (HR per ms: 1.69, p<0.001) was identified as independent predictor of AF recurrence.

conclusionLeft atrial dyssynchrony time is good clinical predictor of recurrence of AF after PVI in patients with paroxysmal and persistent AF.

Indexed as

Atrial FibrillationCatheter AblationEchocardiography, TransesophagealFemaleHeart AtriaHumansMaleMiddle AgedPostoperative PeriodPredictive Value of TestsPulmonary VeinsRecurrenceUltrasonography, Doppler

Identifiers

PMID25252295
PMCPMC5336995

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