Evidence map›Paper›PMID 25252173›Full record

ArticleMagnetic resonance in medicine2015

Simultaneous fat saturation and magnetization transfer contrast imaging with steady-state incoherent sequences.

Feng Zhao, Jon-Fredrik Nielsen, Scott D Swanson, Jeffrey A Fessler, Douglas C Noll

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Feng ZhaoBiomedical Engineering Department, The University of Michigan, Ann Arbor, Michigan, USA.
Jon-Fredrik NielsenBiomedical Engineering Department, The University of Michigan, Ann Arbor, Michigan, USA.
Scott D SwansonRadiology Department, The University of Michigan, Ann Arbor, Michigan, USA.
Jeffrey A FesslerDepartment of Electrical Engineering and Computer Science, The University of Michigan, Ann Arbor, Michigan, USA.
Douglas C NollBiomedical Engineering Department, The University of Michigan, Ann Arbor, Michigan, USA.

Funding

MRI Parallel Excitation for Neuroimaging ApplicationsR01NS058576 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NOLL, DOUGLAS C · 2008 to 2012
$3.0M
Improved Functional MRI Using Balanced SSFP and Parallel TransmissionR21EB012674 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NIELSEN, JON-FREDRIK · 2011 to 2012
$404k
NIBIB NIH HHS R21 EB012674NIBIB NIH HHS R21EB012674NINDS NIH HHS R01 NS058576NINDS NIH HHS R01NS058576
6 · The paper itself

Abstract

purposeThis work combines an n-dimensional fat sat(uration) radiofrequency (RF) pulse with steady-state incoherent (SSI) pulse sequences, e.g., spoiled gradient-echo sequence, to simultaneously produce B0 insensitive fat suppression and magnetization transfer (MT) contrast. This pulse is then referred to as "fat sat and MT contrast pulse." THEORY: We discuss the features of the fat sat and MT contrast pulse and the MT sensitivities of the SSI sequences when combining with fat sat. Moreover, we also introduce an adapted RF spoiling scheme for SSI sequences with fat sat.

methodsSimulations and phantom experiments were conducted to demonstrate the adapted RF spoiling. Fat suppression and MT effects are shown in 3T phantom experiments and in vivo experiments, including brain imaging, cartilage imaging, and angiography.

resultsTo ensure that the sequence reaches steady state, the adapted RF spoiling is required for fat sat SSI sequences. Fat sat and MT contrast pulse works robustly with field inhomogeneity and also produces MT contrasts.

conclusionSSI sequences with fat sat and MT contrast pulse and adapted RF spoiling can robustly produce fat suppressed and MT contrast images in the presence of field inhomogeneity.

Indexed as

Signal Processing, Computer-AssistedAdipose TissueAlgorithmsBrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingPhantoms, ImagingRadio Wavesfat saturationfield inhomogeneitymagnetization transferpulse designRF spoilingspectral-spatial pulse

Identifiers

PMID25252173
PMCPMC4369465

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.