ArticlePloS one2014
Dietary sources of methylated arsenic species in urine of the United States population, NHANES 2003-2010.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Provision of folic acid for reducing arsenic toxicity in arsenic-exposed children and adults.The Cochrane database of systematic reviews · 2021Pooled it
- Urinary arsenic and heart disease mortality in NHANES 2003-2014.Environmental research · 2021Pooled it
- Speciation of Arsenic in Urine from the Health Effects of Arsenic Longitudinal Study (HEALS) Revealing New Arsenic Species and Individual Variability.Environment & health (Washington, D.C.) · 2026Article
- Method validation for (ultra)-trace element concentrations in urine for small sample volumes in large epidemiological studies: application to the population-based epidemiological multi-ethnic study of atherosclerosis (MESA).Analytical methods : advancing methods and applications · 2024Article
- Effects of Dietary Intake of Arsenosugars and Other Organic Arsenic Species on Studies of Arsenic Methylation Efficiency in Humans.Environment & health (Washington, D.C.) · 2023Review
- Biomonitoring California Protocol for Following up on Elevated Levels of Urinary Arsenic.International journal of environmental research and public health · 2023Article
- Inherited genetic effects on arsenic metabolism: A comparison of effects on arsenic species measured in urine and in blood.Environmental epidemiology (Philadelphia, Pa.) · 2022Article
- Associations between rice consumption, arsenic metabolism, and insulin resistance in adults without diabetes.International journal of hygiene and environmental health · 2021Article
- Nutrition, one-carbon metabolism and arsenic methylation.Toxicology · 2021Review
- Arsenic, blood pressure, and hypertension in the Strong Heart Family Study.Environmental research · 2021Article
- Demographic predictors of urinary arsenic in a low-income predominantly Hispanic pregnancy cohort in Los Angeles.Journal of exposure science & environmental epidemiology · 2021Article
- Urinary Arsenic Species are Detectable in Urban Underserved Hispanic/Latino Populations: A Pilot Study from the Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS).International journal of environmental research and public health · 2020Article
- Low level arsenic exposure, B-vitamins, and achievement among Uruguayan school children.International journal of hygiene and environmental health · 2020Article
- Dietary determinants of inorganic arsenic exposure in the Strong Heart Family Study.Environmental research · 2019Article
- Arsenic exposure and serum antibody concentrations to diphtheria and tetanus toxoid in children at age 5: A prospective birth cohort in Bangladesh.Environment international · 2019Article
- Ethnic, geographic and dietary differences in arsenic exposure in the multi-ethnic study of atherosclerosis (MESA).Journal of exposure science & environmental epidemiology · 2019Article
- On the Use of Hair Analysis for Assessing Arsenic Intoxication.International journal of environmental research and public health · 2019Review
- Dietary Therapy for Eosinophilic Esophagitis: Elimination and Reintroduction.Clinical reviews in allergy & immunology · 2018Review
- Evaluation of a Physiologically Based Pharmacokinetic (PBPK) Model for Inorganic Arsenic Exposure Using Data from Two Diverse Human Populations.Environmental health perspectives · 2018Article
- Predictors of Urinary Arsenic Levels among Postmenopausal Danish Women.International journal of environmental research and public health · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundArsenic is an ubiquitous element linked to carcinogenicity, neurotoxicity, as well as adverse respiratory, gastrointestinal, hepatic, and dermal health effects.
objectiveIdentify dietary sources of speciated arsenic: monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA).
methodsAge-stratified, sample-weighted regression of NHANES (National Health and Nutrition Examination Survey) 2003-2010 data (∼8,300 participants ≥6 years old) characterized the association between urinary arsenic species and the additional mass consumed of USDA-standardized food groups (24-hour dietary recall data), controlling for potential confounders.
resultsFor all arsenic species, the rank-order of age strata for median urinary molar concentration was children 6-11 years > adults 20-84 years > adolescents 12-19 years, and for all age strata, the rank-order was DMA > MMA. Median urinary molar concentrations of methylated arsenic species ranged from 0.56 to 3.52 µmol/mol creatinine. Statistically significant increases in urinary arsenic species were associated with increased consumption of: fish (DMA); fruits (DMA, MMA); grain products (DMA, MMA); legumes, nuts, seeds (DMA); meat, poultry (DMA); rice (DMA, MMA); rice cakes/crackers (DMA, MMA); and sugars, sweets, beverages (MMA). And, for adults, rice beverage/milk (DMA, MMA). In addition, based on US (United States) median and 90th percentile consumption rates of each food group, exposure from the following food groups was highlighted: fish; fruits; grain products; legumes, nuts, seeds; meat, poultry; and sugars, sweets, beverages.
conclusionsIn a nationally representative sample of the US civilian, noninstitutionalized population, fish (adults), rice (children), and rice cakes/crackers (adolescents) had the largest associations with urinary DMA. For MMA, rice beverage/milk (adults) and rice cakes/crackers (children, adolescents) had the largest associations.
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