ArticleChemical communications (Cambridge, England)2014
Esterase-activated release of naproxen from supramolecular nanofibres.
Article in Chemical communications (Cambridge, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 44 citations in OpenAlex.
- Synthesis, Characterization and Evaluation of Peptide Nanostructures for Biomedical Applications.Molecules (Basel, Switzerland) · 2021Review
- Inhibition of Antiviral Innate Immunity by Foot-and-Mouth Disease Virus LJournal of virology · 2021Article
- (Macro)molecular self-assembly for hydrogel drug delivery.Advanced drug delivery reviews · 2021Review
- ConjuPepDB: a database of peptide-drug conjugates.Nucleic acids research · 2021Article
- Design, Synthesis, and Nanostructure-Dependent Antibacterial Activity of Cationic Peptide Amphiphiles.ACS applied materials & interfaces · 2019Article
- Facile Protocol for the Synthesis of Self-assembling Polyamine-based Peptide Amphiphiles (PPAs) and Related Biomaterials.Journal of visualized experiments : JoVE · 2018Article
- Engineering responsive supramolecular biomaterials: Toward smart therapeutics.Bioengineering & translational medicine · 2016Review
- (19)F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape.ACS nano · 2016Article
- Smart Nanotransformers with Unique Enzyme-Inducible Structural Changes and Drug Release Properties.Biomacromolecules · 2016Article
- Nucleation and Growth of Ordered Arrays of Silver Nanoparticles on Peptide Nanofibers: Hybrid Nanostructures with Antimicrobial Properties.Journal of the American Chemical Society · 2016Article
- Bio-inspired 3D microenvironments: a new dimension in tissue engineering.Biomedical materials (Bristol, England) · 2016Review
- Building Nanostructures with Drugs.Nano today · 2016Article
- Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses.Veterinary research · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Nanofibre forming peptide amphiphiles were conjugated to naproxen through an esterase-sensitive linker. The amount of naproxen released, in the presence of enzymes, was influenced by the linker conjugating the drug to the supramolecular assembly. In vitro studies showed the anti-inflammatory activity of the released drug was maintained.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.