Trial reportObesity (Silver Spring, Md.)2014
Depression, stress, and weight loss in individuals with metabolic syndrome in SHINE, a DPP translation study.
Trial report in Obesity (Silver Spring, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Weight Loss in Primary Care: a Translation of the Diabetes Prevention Program
Mixed Methods Study Exploring the Impact of Hybrid Closed-loop Systems on Patient Reported Outcomes in People With Type I Diabetes and Their Partners
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Combined Diet and Physical Activity Promotion Programs to Prevent Type 2 Diabetes Among Persons at Increased Risk: A Systematic Review for the Community Preventive Services Task Force.Annals of internal medicine · 2015Pooled it
- Racial disparities in the efficacy of traditional versus acceptance-based behavioral weight loss.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Trial
- Promotora intervention for metabolic and mental health to reduce type 2 diabetes risk: a pilot randomized controlled trial.Scientific reports · 2024Trial
- The association of stressful life events on weight loss efforts among African American breast cancer survivors.Journal of cancer survivorship : research and practice · 2022Trial
- Psychological and behavioral pathways between perceived stress and weight change in a behavioral weight loss intervention.Journal of behavioral medicine · 2021Trial
- Trial
- Lower depression scores associated with greater weight loss among rural black women in a behavioral weight loss program.Translational behavioral medicine · 2017Trial
- Psychosocial moderators of the effect of lifestyle interventions in primary prevention of cardiovascular disease: a scoping review.BMC public health · 2025Article
- Mental health diagnosis attenuates weight loss among older adults in a digital diabetes prevention program.Obesity science & practice · 2023Article
- Changes in Health-Promoting Behaviors and Their Association with Weight Loss, Retention, and Engagement on a Digital Program: Prospective Study.Nutrients · 2022Article
- Weight Change Since Age 20 and the Risk of Cardiovascular Disease Mortality: A Prospective Cohort Study.Journal of atherosclerosis and thrombosis · 2022Article
- Review
- Article
- Mingmu Xiaoyao granules regulate the PI3K/Akt/mTOR signaling pathway to reduce anxiety and depression and reverse retinal abnormalities in rats.Frontiers in pharmacology · 2022Article
- Impact of income and perceived stress on engagement and weight loss outcomes in an online behavioral weight loss program.Journal of behavioral medicine · 2021Article
- Depressive symptom severity as a predictor of attendance in the HOME behavioral weight loss trial.Journal of psychosomatic research · 2020Article
- Depressive symptoms, perceived stress, and metabolic health: The REGARDS study.International journal of obesity (2005) · 2019Article
- Preventive Effects of Escitalopram Against Anxiety-Like Depressive Behaviors in Monosodium Glutamate-Teated Rats Subjected to Partial Hepatectomy.Frontiers in psychology · 2019Article
- Article
- Prediction of the development of metabolic syndrome by the Markov model based on a longitudinal study in Dalian City.BMC public health · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo examine the relationships between elevated depression symptoms (EDS) or stress and weight loss in SHINE, a telephonic, primary-care based, translation of the Diabetes Prevention Program.
methodsN = 257 adults with metabolic syndrome were randomized to individual (IC) or group (CC) phone participation. Weight, depression, anti-depressant use (ADMs), and stress (baseline, 6 months, 1 and 2 years) were assessed. Univariate analyses used linear and logistic regression, t tests for continuous variables and exact tests for categorical variables. Stratified analyses assessed modifiers of effects of depression/stress on weight loss.
resultsApproximately 35% reported EDS, with no change over time. Approximately 28% of all participants used ADMs. Participants with EDS had lower mean % weight loss and a smaller % who achieved ≥5% weight loss. Participants with EDS were less likely to be "completers" (40.1% vs. 61.5%, P = 0.002), coached (48.0% vs. 60.7%, P = 0.049), or log diet/activity (19.4% vs. 42.7%, P < 0.001), behaviors related to weight loss. Results were similar for high stress. ADM use had no independent effect on weight loss.
conclusionsIndividuals with metabolic syndrome and EDS and/or high stress were less likely to lose significant weight. Pre-intervention depression and stress screening to intervene may improve weight loss.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.