ArticlePloS one2014
Hemispheric asymmetry in new neurons in adulthood is associated with vocal learning and auditory memory.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- The Adult Neurogenesis Theory of Alzheimer's Disease Predicts Where Tauopathy Develops in the Brain.International journal of molecular sciences · 2026Review
- Seasonal patterns of neurogenesis in European starlings (Sturnus vulgaris) are region- and sex-specific.Journal of neuroendocrinology · 2025Article
- Daily high doses of atorvastatin alter neuronal morphology in a juvenile songbird model.PloS one · 2025Article
- Novel sound exposure drives dynamic changes in auditory lateralization that are associated with perceptual learning in zebra finches.Communications biology · 2023Article
- Effects of the depletion of neural progenitors by focal X-ray irradiation on song production and perception in canaries.Scientific reports · 2023Article
- Aromatase and nonaromatase neurons in the zebra finch secondary auditory forebrain are indistinct in their song-driven gene induction and intrinsic electrophysiological properties.The European journal of neuroscience · 2021Article
- Unilateral vocal nerve resection alters neurogenesis in the avian song system in a region-specific manner.PloS one · 2021Article
- Lateralization of social signal brain processing correlates with the degree of social integration in a songbird.Scientific reports · 2020Article
- Testosterone synthesis in the female songbird brain.Hormones and behavior · 2020Article
- Auditory learning in an operant task with social reinforcement is dependent on neuroestrogen synthesis in the male songbird auditory cortex.Hormones and behavior · 2020Article
- Hemispheric asymmetry of calbindin-positive neurons is associated with successful song imitation.Brain research · 2020Article
- Bilateral brain activity in auditory regions is necessary for successful vocal learning in songbirds.Neuroscience letters · 2020Article
- Cerebral lateralisation during signed and spoken language production in children born deaf.Developmental cognitive neuroscience · 2019Article
- Influence of early-life nutritional stress on songbird memory formation.Proceedings. Biological sciences · 2018Article
- Topography and Lateralized Effect of Acute Aromatase Inhibition on Auditory Processing in a Seasonal Songbird.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- HDAC3 Inhibitor RGFP966 Modulates Neuronal Memory for Vocal Communication Signals in a Songbird Model.Frontiers in systems neuroscience · 2017Article
- Mirrored patterns of lateralized neuronal activation reflect old and new memories in the avian auditory cortex.Neuroscience · 2016Article
- Neural responses in songbird forebrain reflect learning rates, acquired salience, and stimulus novelty after auditory discrimination training.Journal of neurophysiology · 2015Article
Corrections and comments
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Authors and funding
6 authors.
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Abstract
Many brain regions exhibit lateral differences in structure and function, and also incorporate new neurons in adulthood, thought to function in learning and in the formation of new memories. However, the contribution of new neurons to hemispheric differences in processing is unknown. The present study combines cellular, behavioral, and physiological methods to address whether 1) new neuron incorporation differs between the brain hemispheres, and 2) the degree to which hemispheric lateralization of new neurons correlates with behavioral and physiological measures of learning and memory. The songbird provides a model system for assessing the contribution of new neurons to hemispheric specialization because songbird brain areas for vocal processing are functionally lateralized and receive a continuous influx of new neurons in adulthood. In adult male zebra finches, we quantified new neurons in the caudomedial nidopallium (NCM), a forebrain area involved in discrimination and memory for the complex vocalizations of individual conspecifics. We assessed song learning and recorded neural responses to song in NCM. We found significantly more new neurons labeled in left than in right NCM; moreover, the degree of asymmetry in new neuron numbers was correlated with the quality of song learning and strength of neuronal memory for recently heard songs. In birds with experimentally impaired song quality, the hemispheric difference in new neurons was diminished. These results suggest that new neurons may contribute to an allocation of function between the hemispheres that underlies the learning and processing of complex signals.
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