Evidence map›Paper›PMID 25251047›Full record

ArticleMedicine and science in sports and exercise2015

Strength fitness and body weight status on markers of cardiometabolic health.

Christian K Roberts, Mary M Lee, Michael Katiraie, Shannon L Krell, Siddhartha S Angadi, Michael K Chronley, Christopher S Oh, Vicent Ribas, Ryan A Harris, Andrea L Hevener and 1 more

Abstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Assessments of endothelial function and arterial stiffness are reproducible in patients with COPD.International journal of chronic obstructive pulmonary disease · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christian K Roberts1Exercise Physiology and Metabolic Disease Research Laboratory, Translational Sciences Section, School of Nursing, University of California, Los Angeles, CA; 2Division of Endocrinology, Diabetes, and Hypertension, David Geffen School of Medicine, University of California, Los Angeles, CA; 3Georgia Prevention Institute, Georgia Health Sciences University, Augusta, GA; and 4David Geffen School of Medicine, University of California, Los Angeles, CA.
Mary M Lee
Michael Katiraie
Shannon L Krell
Siddhartha S Angadi
Michael K Chronley
Christopher S Oh
Vicent Ribas
Ryan A Harris
Andrea L Hevener
Daniel M Croymans

Funding

UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
Vascular function, cardiovascular disease biomarkers and the Latino paradoxP50HL105188 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KAPLAN, ROBERT M · 2010 to 2014
$9.9M
Glycemic Load and Resistance Training on Endothelial Function and InflammationR01DK090406 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CARPENTER, CATHERINE L, GO, VAY LIANG W · 2011 to 2014
$2.7M
ERalpha and the metabolic syndromeR01DK089109 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HEVENER, ANDREA L · 2011 to 2014
$1.4M
NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1TR000124NHLBI NIH HHS P50 HL105188NHLBI NIH HHS P50HL105188NIDDK NIH HHS R01 DK089109NIDDK NIH HHS R01 DK090406NIDDK NIH HHS R01DK090406
6 · The paper itself

Abstract

introductionRecent evidence suggests that resistance training (RT) may reduce metabolic and cardiovascular disease risk. We investigated whether overweight/class I obese individuals by BMI classification with high strength fitness exhibit cardiovascular/metabolic phenotypes similar to those overweight/obese and untrained or those normal-weight with high strength fitness.

methodsA total of 90 young males were categorized into three groups: overweight untrained (OU, n = 30, BMI > 27 kg·m⁻²), overweight trained (OT, n = 30, BMI > 27 kg·m⁻², RT ≥ 4 d·wk⁻¹), and normal-weight trained (NT, n = 30, BMI < 25 kg·m⁻², RT ≥ 4 d·wk⁻¹). Participants were assessed for strength, body composition, central/peripheral blood pressures, arterial stiffness, and markers of cardiovascular and metabolic health.

resultsBody weight was similar in OT and OU and greater than NT (P < 0.00001), and fat mass was different in all groups (P < 0.001). Compared to OU, NT and OT groups exhibited higher relative strength (NT = 46.7%, OT = 44.4%, P < 0.00001), subendocardial viability ratio (NT = 21.0%, P < 0.001; OT = 17.0%, P < 0.01), and lower brachial/central blood pressures (NT P < 0.001; OT P ≤ 0.05); augmentation index and pulse-wave velocity were lower only in OT (P < 0.05). Total cholesterol, low-density lipoprotein (NT P < 0.01, OT P < 0.05), triglycerides (NT = -50.4%, OT = -41.8%, P < 0.001), oxidized LDL (NT = -39.8%, OT = -31.8%, P < 0.001), and CRP (NT = -63.7%, OT = -67.4%, P < 0.01) levels were lower and high-density lipoprotein (NT = 26.9%, OT = 21.4%, P < 0.001) levels were higher in NT and OT compared to OU. NT and OT also exhibited lower amylin (NT = -55.8%, OT = -40.8%) and leptin (NT = -84.6%, OT = -59.4%) and higher adiponectin (NT = 87.5%, P < 0.001; OT = 78.1%, P < 0.01) and sex hormone-binding globulin (NT = 124.4%, OT = 92.3%, P < 0.001). Despite greater total and trunk fat in OT compared with NT, other than glucose and insulin, which were lower in NT than in both OT and OU (OT P < 0.01, OU P < 0.001), OT did not exhibit any impaired biomarker/phenotype compared to NT.

conclusionsThese findings provide evidence that overweight/class I obese individuals with high strength fitness exhibit metabolic/cardiovascular risk profiles similar to normal-weight, fit individuals rather than overweight/class I obese unfit individuals. Strength training may be important to metabolic and cardiovascular health.

Indexed as

Body WeightHealth Status IndicatorsResistance TrainingAdolescentAdultBlood Chemical AnalysisBlood PressureBody CompositionCross-Sectional StudiesHumansMaleMuscle StrengthObesityOverweightPhenotypePhysical Fitness

Identifiers

PMID25251047
PMCPMC5866050

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.