ArticleThe Journal of clinical endocrinology and metabolism2015
The association between abdominal muscle and type II diabetes across weight categories in diverse post-menopausal women.
Article in The Journal of clinical endocrinology and metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
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Who cites it
16 citing papers in PubMed.
- Relationship between rectus abdominis muscle thickness and metabolic syndrome in middle-aged men.PloS one · 2017Trial
- Associations of Abdominal Muscle Density and Area and Incident Cardiovascular Disease, Coronary Heart Disease, and Stroke: The Multi-Ethnic Study of Atherosclerosis.Journal of the American Heart Association · 2024Article
- Evidence and consensus-based clinical practice guidelines for management of overweight and obesity in midlife women: An AIIMS-DST initiative.Journal of family medicine and primary care · 2022Review
- Association of abdominal muscle area and density with glucose regulation: The multi-ethnic study of atherosclerosis (MESA).Diabetes/metabolism research and reviews · 2022Article
- Relative associations of abdominal and thigh compositions with cardiometabolic diseases in African Caribbean men.Obesity science & practice · 2021Article
- Muscle area and density and risk of all-cause mortality: The Multi-Ethnic Study of Atherosclerosis.Metabolism: clinical and experimental · 2020Article
- Nonalcoholic Fatty Liver Disease and Sarcopenia: Where Do We Stand?Canadian journal of gastroenterology & hepatology · 2020Review
- Letter: Association of Thigh Muscle Mass with Insulin Resistance and Incident Type 2 Diabetes Mellitus in Japanese Americans (Diabetes Metab J 2018;42:488-95).Diabetes & metabolism journal · 2019Article
- Engaging the ASEAN Diaspora: Type 2 Diabetes Prevalence, Pathophysiology, and Unique Risk Factors among Filipino Migrants in the United States.Journal of the ASEAN Federation of Endocrine Societies · 2019Article
- Association of Thigh Muscle Mass with Insulin Resistance and Incident Type 2 Diabetes Mellitus in Japanese Americans.Diabetes & metabolism journal · 2018Article
- Percentiles for skeletal muscle index, area and radiation attenuation based on computed tomography imaging in a healthy Caucasian population.European journal of clinical nutrition · 2018Article
- Effects of combination of change in visceral fat and thigh muscle mass on the development of type 2 diabetes.Diabetes research and clinical practice · 2017Article
- A comprehensive approach to the molecular determinants of lifespan using a Boolean model of geroconversion.Aging cell · 2016Article
- Association of Muscle Mass, Area, and Strength With Incident Diabetes in Older Adults: The Health ABC Study.The Journal of clinical endocrinology and metabolism · 2016Article
- Prescribing Pattern of Oral Antihyperglycaemic Drugs, Rationality and Adherence to American Diabetes Association (ADA) Treatment Guidelines among Type 2 Diabetes Mellitus (T2DM) Postmenopausal Women.Journal of clinical and diagnostic research : JCDR · 2016Article
- Type II diabetes disparities in diverse women: the potential roles of body composition, diet and physical activity.Women's health (London, England) · 2015Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
contextDespite the key role of muscle in glucose regulation, little is known about the association between muscle area and prevalence of metabolic disorders, or the role low muscle may play in normal weight metabolic obesity.
objectiveThe objective was to assess the independent associations between both abdominal muscle and fat depositions (measured by computed tomography) and the prevalence of type II diabetes, and to explore the modifying role of weight category.
designWe conducted a cross-sectional analysis of the 2001-2002 visit for the Rancho Bernardo Study, Filipino Women's Health Study, and Health Assessment Study of African American Women. SETTING AND
participantsParticipants were 392 community-dwelling older women (mean age = 64) free of clinical cardiovascular disease.
main outcome measureThe main outcome was prevalence of type II diabetes, defined as use of anti-diabetes medication, fasting plasma glucose ≥ 126 mg/dL, and/or OGTT ≥ 200 mg/dL.
resultsAdjusting for demographics, hypertension, estrogen use, lipids, smoking, physical activity, visceral fat area, and height, a greater muscle-to-total abdominal area ratio (MAR) was associated with lower odds of diabetes [OR = 0.63 per standard deviation, 95% CI (0.43-0.92), p = .02]. Higher visceral fat was associated with greater odds of diabetes in fully adjusted models including total muscle area [OR = 1.48, 95% CI (1.09, 2.01), p = .01]. Associations between MAR and diabetes were stronger for normal weight (BMI 18.5-24.9; OR = 0.32) than overweight/obese women (BMI ≥ 25, OR = 0.71, p-for-interaction = 0.046). Associations with visceral fat did not differ by BMI (p-for-interaction = 0.71).
conclusionsIn older women, abdominal muscle area is inversely associated with type II diabetes independent of visceral adiposity, particularly for normal weight women.
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