SynthesisBioMed research international2014
Association of a miRNA-137 polymorphism with schizophrenia in a Southern Chinese Han population.
Synthesis in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Association of MIR137 rs1625579 polymorphisms with cognitive function in patients with untreated first-episode depression.Acta neurologica Belgica · 2026Article
- The role of microRNAs in executive functions: a comprehensive review and bioinformatics analysis of human and animal studies.Molecular psychiatry · 2026Review
- Dysregulation of MiRNAs in schizophrenia in an Egyptian patient population.Scientific reports · 2025Article
- Role of miRNA Gene Variants (miR-22 and miR-155) as the Factors Affecting Susceptibility to Panic Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024Article
- The Role of microRNA in Schizophrenia: A Scoping Review.International journal of molecular sciences · 2024Article
- Association between Mir-17-92 gene promoter polymorphisms and depression in a Chinese population.BMC medical genomics · 2024Article
- Schizophrenia plausible protective effect of microRNA-137 is potentially related to estrogen and prolactin in female patients.Frontiers in psychiatry · 2023Article
- Glyoxalase 1 Confers Susceptibility to Schizophrenia: From Genetic Variants to Phenotypes of Neural Function.Frontiers in molecular neuroscience · 2021Article
- Sex-Specific Associations ofFrontiers in genetics · 2021Article
- Genetic Variability of TCF4 in Schizophrenia of Southern Chinese Han Population: A Case-Control Study.Frontiers in genetics · 2019Article
- Dysregulation of miRNA and its potential therapeutic application in schizophrenia.CNS neuroscience & therapeutics · 2018Review
- Non-Coding RNA as Novel Players in the Pathophysiology of Schizophrenia.Non-coding RNA · 2018Review
- microRNAs Sculpt Neuronal Communication in a Tight Balance That Is Lost in Neurological Disease.Frontiers in molecular neuroscience · 2018Review
- Association ofFrontiers in psychiatry · 2018Article
- Polymorphism in schizophrenia risk geneNeuroImage. Clinical · 2018Article
- The rs1625579 T>G polymorphism in theInfection and drug resistance · 2018Article
- Association of the Synapse-Associated Protein 97 (Frontiers in psychiatry · 2018Article
- Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese.Scientific reports · 2017Article
- Association of Polymorphisms of the Receptor for Advanced Glycation Endproducts Gene with Schizophrenia in a Han Chinese Population.BioMed research international · 2017Article
- Genomic Editing of Non-Coding RNA Genes with CRISPR/Cas9 Ushers in a Potential Novel Approach to Study and Treat Schizophrenia.Frontiers in molecular neuroscience · 2017Review
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Both genome wide association study (GWAS) and biochemical studies of Caucasian populations indicate a robust association between the miR-137 genetic variant rs1625579 and schizophrenia, but inconsistent results have been reported. To assay the association between this variant and schizophrenia, we genotyped 611 schizophrenic patients from Southern Chinese Han population for the risk single nucleotide polymorphism (SNP) rs1625579 using the SNaPshot technique and compared the clinical profiles of different genotypes. Additionally, a meta-analysis was performed using the combined sample groups from five case-control publications and the present study. Both the genotype and allele distributions of the rs1625579 SNP were significantly different between patients and controls (P = 0.036 and 0.026, SNP). TT genotype carriers showed slightly lower Brief Assessment of Cognition in Schizophrenia- (BACS-) derived working memory performance than G carriers (15.58 ± 9.56 versus 19.71 ± 8.18, P = 0.045). In the meta-analysis, we observed a significant association between rs1625579 and schizophrenia under different genetic models (all P < 0.05). The results of our study and meta-analysis provide convincing evidence that rs1625579 is significantly associated with schizophrenia. Furthermore, the miR-137 polymorphism influences the working memory performance of schizophrenic patients in a Chinese Han population.
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