ArticleFrontiers in plant science2014
Plant chemical biology: are we meeting the promise?
Article in Frontiers in plant science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- Chemical Biology Meets Metabolomics: The Response of Barley Seedlings to 3,5-Dichloroanthranilic Acid, a Resistance Inducer.Molecules (Basel, Switzerland) · 2025Article
- Chemical screening approach using single leaves identifies compounds that affect cold signaling in Arabidopsis.Plant physiology · 2023Article
- An open source plant kinase chemogenomics set.Plant direct · 2022Article
- A reactive oxygen species CaThe New phytologist · 2022Article
- Proteome-wide cellular thermal shift assay reveals unexpected cross-talk between brassinosteroid and auxin signaling.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Identification of stomatal-regulating molecules from de novo arylamine collection through aromatic C-H amination.Scientific reports · 2022Article
- Bioimaging tools move plant physiology studies forward.Frontiers in plant science · 2022Article
- Histidine kinase inhibitors impair shoot regeneration inFrontiers in plant science · 2022Article
- The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases.The Plant journal : for cell and molecular biology · 2021Article
- A phenotype-directed chemical screen identifies ponalrestat as an inhibitor of the plant flavin monooxygenase YUCCA in auxin biosynthesis.The Journal of biological chemistry · 2019Article
- Remove, Recycle, Degrade: Regulating Plasma Membrane Protein Accumulation.The Plant cell · 2019Review
- Understanding the language of drugged plants.Nature chemical biology · 2019Article
- The Root Growth-Regulating Brevicompanine Natural Products Modulate the Plant Circadian Clock.ACS chemical biology · 2017Article
- Clathrin in plant defense signaling and execution.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Chemical Genetics Uncovers Novel Inhibitors of Lignification, Including p-Iodobenzoic Acid Targeting CINNAMATE-4-HYDROXYLASE.Plant physiology · 2016Article
- Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism.Biochemical Society transactions · 2016Review
- Facile high-throughput forward chemical genetic screening by in situ monitoring of glucuronidase-based reporter gene expression in Arabidopsis thaliana.Frontiers in plant science · 2015Article
- Considerations for designing chemical screening strategies in plant biology.Frontiers in plant science · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As an early adopter of plant chemical genetics to the study of endomembrane trafficking, we have observed the growth of small molecule approaches. Within the field, we often describe the strengths of the approach in a broad, generic manner, such as the ability to address redundancy and lethality. But, we are now in a much better position to evaluate the demonstrated value of the approach based on examples. In this perspective, we offer an assessment of chemical genetics in plants and where its applications may be of particular utility from the perspective of the cell biologist. Beyond this, we suggest areas to be addressed to provide broader access and enhance the effectiveness of small molecule approaches in plant biology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.