Evidence map›Paper›PMID 25250036›Full record

ArticleFrontiers in plant science2014

Flavone-rich maize: an opportunity to improve the nutritional value of an important commodity crop.

María I Casas, Silvia Duarte, Andrea I Doseff, Erich Grotewold

Open access · goldAbstract read
In one paragraph

Article in Frontiers in plant science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 70 citations in OpenAlex.

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  19. Frontiers in plant science · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

María I CasasCenter for Applied Plant Sciences, The Ohio State University Columbus, OH, USA ; Molecular Cellular and Developmental Biology Graduate Program, The Ohio State University Columbus, OH, USA ; Department of Molecular Genetics, The Ohio State University Columbus, OH, USA.
Silvia DuarteDepartment of Molecular Genetics, The Ohio State University Columbus, OH, USA ; Division of Pulmonary, Allergy, Critical Care, and Sleep, Department of Internal Medicine, Heart and Lung Research Institute, The Ohio State University Columbus, OH, USA.
Andrea I DoseffDepartment of Molecular Genetics, The Ohio State University Columbus, OH, USA ; Division of Pulmonary, Allergy, Critical Care, and Sleep, Department of Internal Medicine, Heart and Lung Research Institute, The Ohio State University Columbus, OH, USA.
Erich GrotewoldCenter for Applied Plant Sciences, The Ohio State University Columbus, OH, USA ; Department of Molecular Genetics, The Ohio State University Columbus, OH, USA.
Lung Institute · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Agricultural outputs have resulted in food production continuously expanding. To satisfy the needs of a fast growing human population, higher yields, more efficient food processing, and food esthetic value, new crop varieties with higher caloric intake have and continue to be developed, but which lack many phytochemicals important for plant protection and adequate human nutrition. The increasing incidence of chronic diseases such as obesity, diabetes and cardiovascular diseases, combined with social disparity worldwide prompted the interest in developing enhanced crops that can simultaneously address the two sides of the current malnutrition sword, increasing yield while providing added nutritional value. Flavones, phytochemicals associated with the beneficial effects of the Mediterranean diet, have potent anti-inflammatory and anti-carcinogenic activities. However, many Mediterranean diet-associated vegetables are inaccessible, or lowly consumed, in many parts of the world. Maize is the most widely grown cereal crop, yet most lines used for hybrid maize production lack flavones. As a first step toward a sustainable strategy to increasing the nutritional value of maize-based diets, we investigated the accumulation and chemical properties of flavones in maize seeds of defined genotypes. We show that the pericarps of the P1-rr genotype accumulate flavones at levels comparable to those present in some flavone-rich vegetables, and are mostly present in their C- and O-glycosylated forms. Some of these glycosides can be readily converted into the corresponding more active health beneficial aglycones during food processing. Our results provide evidence that nutritionally beneficial flavones could be re-introduced into elite lines to increase the dietary benefits of maize.

Indexed as

cancerinflammationmaizemetabolismnutritionnutritional disparity

Identifiers

PMID25250036
PMCPMC4157551
OpenAlexW2145634846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.