Evidence map›Paper›PMID 25249784›Full record

ArticleGenetics and molecular biology2014

Large-scale analysis of NBS domain-encoding resistance gene analogs in Triticeae.

Dhia Bouktila, Yosra Khalfallah, Yosra Habachi-Houimli, Maha Mezghani-Khemakhem, Mohamed Makni, Hanem Makni

Open access · goldAbstract read
In one paragraph

Article in Genetics and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Disease Resistance Gene Analogs (RGAs) in Plants.International journal of molecular sciences · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dhia BouktilaUnité de Recherche Génomique des Insectes Ravageurs des Cultures d'Intérêt Agronomique , Faculté des Sciences de Tunis, Université de Tunis El Manar , El Manar, Tunis , Tunisia . ; Institut Supérieur de Biotechnologie de Béja , Université de Jendouba , Béja , Tunisia .
Yosra KhalfallahUnité de Recherche Génomique des Insectes Ravageurs des Cultures d'Intérêt Agronomique , Faculté des Sciences de Tunis, Université de Tunis El Manar , El Manar, Tunis , Tunisia .
Yosra Habachi-HouimliUnité de Recherche Génomique des Insectes Ravageurs des Cultures d'Intérêt Agronomique , Faculté des Sciences de Tunis, Université de Tunis El Manar , El Manar, Tunis , Tunisia .
Maha Mezghani-KhemakhemUnité de Recherche Génomique des Insectes Ravageurs des Cultures d'Intérêt Agronomique , Faculté des Sciences de Tunis, Université de Tunis El Manar , El Manar, Tunis , Tunisia .
Mohamed MakniUnité de Recherche Génomique des Insectes Ravageurs des Cultures d'Intérêt Agronomique , Faculté des Sciences de Tunis, Université de Tunis El Manar , El Manar, Tunis , Tunisia .
Hanem MakniUnité de Recherche Génomique des Insectes Ravageurs des Cultures d'Intérêt Agronomique , Faculté des Sciences de Tunis, Université de Tunis El Manar , El Manar, Tunis , Tunisia . ; Institut Supérieur de l'Animation pour la Jeunesse et la Culture , Université de Tunis , Bir-El-Bey , Tunisia .
Tunis El Manar University · TNTunis University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins containing nucleotide binding sites (NBS) encoded by plant resistance genes play an important role in the response of plants to a wide array of pathogens. In this paper, an in silico search was conducted in order to identify and characterize members of NBS-encoding gene family in the tribe of Triticeae. A final dataset of 199 sequences was obtained by four search methods. Motif analysis confirmed the general structural organization of the NBS domain in cereals, characterized by the presence of the six commonly conserved motifs: P-loop, RNBS-A, Kinase-2, Kinase-3a, RNBS-C and GLPL. We revealed the existence of 11 distinct distribution patterns of these motifs along the NBS domain. Four additional conserved motifs were shown to be significantly present in all 199 sequences. Phylogenetic analyses, based on genetic distance and parsimony, revealed a significant overlap between Triticeae sequences and Coiled coil-Nucleotide binding site-Leucine rich repeat (CNL)-type functional genes from monocotyledons. Furthermore, several Triticeae sequences belonged to clades containing functional homologs from non Triticeae species, which has allowed for these sequences to be functionally assigned. The findings reported, in this study, will provide a strong groundwork for the isolation of candidate R-genes in Triticeae crops and the understanding of their evolution.

Indexed as

data miningNBS domainphylogenyplant resistance genesTriticeae

Identifiers

PMID25249784
PMCPMC4171767
OpenAlexW2003496316

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.