ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2014
Association between electrocardiographic findings and cardiac dysfunction in adult isolated traumatic brain injury.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 46 citations in OpenAlex.
- Neurocardiac consequences of traumatic brain injury: integrating neuroimmune, autonomic, and cerebrovascular mechanisms.Frontiers in immunology · 2026Review
- A Hybrid Bidirectional Deep Learning Model Using HRV for Prediction of ICU Mortality Risk in TBI Patients.Journal of healthcare informatics research · 2025Article
- Early Autonomic Dysfunction in Traumatic Brain Injury: An Article Review on the Impact on Multiple Organ Dysfunction.Journal of clinical medicine · 2025Review
- Cardiac Injury After Traumatic Brain Injury: Clinical Consequences and Management.Neurocritical care · 2024Article
- Correlation of head injury with ECG and echo changes.Surgical neurology international · 2024Article
- Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice.PloS one · 2023Article
- A prospective exploratory study to assess echocardiographic changes in patients with supratentorial tumors - Effect of craniotomy and tumor decompression.Surgical neurology international · 2023Article
- Role of electrocardiogram findings in predicting 48-h mortality in patients with traumatic brain injury.BMC neurology · 2022Observational
- Role of Bevacizumab on Vascular Endothelial Growth Factor in Apolipoprotein E Deficient Mice after Traumatic Brain Injury.International journal of molecular sciences · 2022Article
- The Clinical Differences of Patients With Traumatic Brain Injury in Plateau and Plain Areas.Frontiers in neurology · 2022Article
- Improving Understanding and Outcomes of Traumatic Brain Injury Using Bidirectional Translational Research.Journal of neurotrauma · 2020Review
- The Short-Term Effects of Isolated Traumatic Brain Injury on the Heart in Experimental Healthy Rats.Neurocritical care · 2020Article
- Human umbilical cord blood cells rescued traumatic brain injury-induced cardiac and neurological deficits.Annals of translational medicine · 2020Article
- Splenectomy does not affect the development of pneumonia following severe traumatic brain injury.Brain, behavior, & immunity - health · 2020Article
- The Association of Early Electrocardiographic Abnormalities With Brain Injury Severity and Outcome in Severe Traumatic Brain Injury.Frontiers in neurology · 2020Article
- A pilot study evaluating a simple cardiac dysfunction score to predict complications and survival among critically-ill patients with traumatic brain injury.Journal of critical care · 2019Article
- Cerebral Perfusion Pressure Directed-Therapy Modulates Cardiac Dysfunction After Traumatic Brain Injury to Influence Cerebral Autoregulation in Pigs.Neurocritical care · 2019Article
- Propranolol protects cerebral autoregulation and reduces hippocampal neuronal cell death through inhibition of interleukin-6 upregulation after traumatic brain injury in pigs.British journal of anaesthesia · 2019Article
- Traumatic Brain Injury Leads to Accelerated Atherosclerosis in Apolipoprotein E Deficient Mice.Scientific reports · 2018Article
- Hypertension After Severe Traumatic Brain Injury: Friend or Foe?Journal of neurosurgical anesthesiology · 2017Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
Abstract
introductionAbnormal electrocardiographic (ECG) findings can be seen in traumatic brain injury (TBI) patients. ECG may be an inexpensive tool to identify patients at high risk for developing cardiac dysfunction after TBI. The aim of this study was to examine abnormal ECG findings after isolated TBI and their association with true cardiac dysfunction, based on echocardiogram.
methodsData from adult patients with isolated TBI between 2003 and 2010 was retrospectively examined. Inclusion criteria included the presence of a 12-lead ECG within 24 h of admission and a formal echocardiographic examination within 72 h of admission after TBI. Patients with preexisting cardiac disease were excluded. Baseline clinical characteristics, 12-lead ECG, and echocardiogram report were abstracted. Logistic regression was used to identify the relationship of specific ECG abnormalities with cardiac dysfunction.
resultsWe examined data from 59 patients with isolated TBI who underwent 12-lead ECG and echocardiographic evaluation. In this cohort, 13 (22%) patients had tachycardia (heart rate >100 bpm), 25 (42.4%) patients had a prolonged QTc, and 6 (10.2%) patients had morphologic end-repolarization abnormalities (MERA), with each having an association with abnormal echocardiographic findings: Odds ratios (and 95% confidence intervals) were 4.14 (1.02-17.05), 9.0 (1.74-46.65), and 5.63 (1.96-32.94), respectively. Ischemic-like ECG changes were not associated with echocardiographic abnormalities.
conclusionsRepolarization abnormalities (prolonged QTc and MERA), but not ischemic-like ECG changes, are associated with cardiac dysfunction after isolated TBI. 12-lead ECG may be an inexpensive screening tool to evaluate isolated TBI patients for cardiac dysfunction prior to more expensive or invasive studies.
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