Evidence map›Paper›PMID 25249626›Full record

ArticleNucleic acids research2014

Insyght: navigating amongst abundant homologues, syntenies and gene functional annotations in bacteria, it's that symbol!

Thomas Lacroix, Valentin Loux, Annie Gendrault, Mark Hoebeke, Jean-François Gibrat

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Thomas LacroixINRA, UR 1077 Mathématique Informatique et Génome, 78352 Jouy-en-Josas, France thomas.lacroix@jouy.inra.fr.
Valentin LouxINRA, UR 1077 Mathématique Informatique et Génome, 78352 Jouy-en-Josas, France.
Annie GendraultINRA, UR 1077 Mathématique Informatique et Génome, 78352 Jouy-en-Josas, France.
Mark HoebekeCNRS, UPMC, FR2424, ABiMS, Station Biologique, 29680 Roscoff, France.
Jean-François GibratINRA, UR 1077 Mathématique Informatique et Génome, 78352 Jouy-en-Josas, France.
Mathématiques et Informatique Appliquées du Génome à l'Environnement · FRStation Biologique de Roscoff · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput techniques have considerably increased the potential of comparative genomics whilst simultaneously posing many new challenges. One of those challenges involves efficiently mining the large amount of data produced and exploring the landscape of both conserved and idiosyncratic genomic regions across multiple genomes. Domains of application of these analyses are diverse: identification of evolutionary events, inference of gene functions, detection of niche-specific genes or phylogenetic profiling. Insyght is a comparative genomic visualization tool that combines three complementary displays: (i) a table for thoroughly browsing amongst homologues, (ii) a comparator of orthologue functional annotations and (iii) a genomic organization view designed to improve the legibility of rearrangements and distinctive loci. The latter display combines symbolic and proportional graphical paradigms. Synchronized navigation across multiple species and interoperability between the views are core features of Insyght. A gene filter mechanism is provided that helps the user to build a biologically relevant gene set according to multiple criteria such as presence/absence of homologues and/or various annotations. We illustrate the use of Insyght with scenarios. Currently, only Bacteria and Archaea are supported. A public instance is available at http://genome.jouy.inra.fr/Insyght. The tool is freely downloadable for private data set analysis.

Indexed as

Genes, BacterialMolecular Sequence AnnotationSyntenyComputer GraphicsData MiningGenes, ArchaealGenomicsSequence Homology, Nucleic AcidSoftware

Identifiers

PMID25249626
PMCPMC4245967
OpenAlexW2028897438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.