ArticleCerebral cortex (New York, N.Y. : 1991)2015
Neuroanatomy of Individual Differences in Language in Adult Males with Autism.
Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review of Brainstem Contributions to Autism Spectrum Disorder.Frontiers in integrative neuroscience · 2021Pooled it
- Typical versus delayed speech onset influences verbal reporting of autistic interests.Molecular autism · 2017Trial
- Brain structural morphometry in non-musicians with superior pitch identification ability.Scientific reports · 2026Article
- Sensory-movement underpinnings of lifelong neurodivergence: getting a grip on autism.Frontiers in integrative neuroscience · 2025Article
- Cross-sectional and longitudinal neuroanatomical profiles of distinct clinical (adaptive) outcomes in autism.Molecular psychiatry · 2023Article
- Sex differences of language abilities of preschool children with autism spectrum disorder and their anatomical correlation with Broca and Wernicke areas.Frontiers in pediatrics · 2022Article
- Rethinking Our Concepts and Assumptions About Autism.Frontiers in psychiatry · 2022Article
- Barriers to Autism Spectrum Disorder Diagnosis for Young Women and Girls: a Systematic Review.Review journal of autism and developmental disorders · 2021Review
- Autism spectrum heterogeneity: fact or artifact?Molecular psychiatry · 2020Review
- Treatment of Folate Metabolism Abnormalities in Autism Spectrum Disorder.Seminars in pediatric neurology · 2020Review
- Semantic Processing in Autism Spectrum Disorders Is Associated With the Timing of Language Acquisition: A Magnetoencephalographic Study.Frontiers in human neuroscience · 2020Article
- Clinical Profile of Autism Spectrum Disorder in a Pediatric Population from Northern Mexico.Journal of autism and developmental disorders · 2019Article
- Subtyping the Autism Spectrum Disorder: Comparison of Children with High Functioning Autism and Asperger Syndrome.Journal of autism and developmental disorders · 2019Article
- Dissociations in the neural substrates of language and social functioning in autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2018Article
- Assessing Autism in Adults: An Evaluation of the Developmental, Dimensional and Diagnostic Interview-Adult Version (3Di-Adult).Journal of autism and developmental disorders · 2018Article
- Gyrification changes are related to cognitive strengths in autism.NeuroImage. Clinical · 2018Article
- Network-specific sex differentiation of intrinsic brain function in males with autism.Molecular autism · 2018Article
- Increased Left Inferior Temporal Gyrus Was Found in Both Low Function Autism and High Function Autism.Frontiers in psychiatry · 2018Article
- Reduced Gray Matter Volume in the Social Brain Network in Adults with Autism Spectrum Disorder.Frontiers in human neuroscience · 2017Article
- Cerebellar gray matter differentiates children with early language delay in autism.Autism research : official journal of the International Society for Autism Research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
One potential source of heterogeneity within autism spectrum conditions (ASC) is language development and ability. In 80 high-functioning male adults with ASC, we tested if variations in developmental and current structural language are associated with current neuroanatomy. Groups with and without language delay differed behaviorally in early social reciprocity, current language, but not current autistic features. Language delay was associated with larger total gray matter (GM) volume, smaller relative volume at bilateral insula, ventral basal ganglia, and right superior, middle, and polar temporal structures, and larger relative volume at pons and medulla oblongata in adulthood. Despite this heterogeneity, those with and without language delay showed significant commonality in morphometric features when contrasted with matched neurotypical individuals (n = 57). In ASC, better current language was associated with increased GM volume in bilateral temporal pole, superior temporal regions, dorsolateral fronto-parietal and cerebellar structures, and increased white matter volume in distributed frontal and insular regions. Furthermore, current language-neuroanatomy correlation patterns were similar across subgroups with or without language delay. High-functioning adult males with ASC show neuroanatomical variations associated with both developmental and current language characteristics. This underscores the importance of including both developmental and current language as specifiers for ASC, to help clarify heterogeneity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.