Evidence map›Paper›PMID 25248710›Full record

ReviewZhongguo fei ai za zhi = Chinese journal of lung cancer2014

[Advancement of relationship between metabolic alteration 
in cancer-associated fibroblasts and tumor progression in lung cancer].

Heng Du, Guowei Che

Open access · greenAbstract readEnglish AbstractReview
In one paragraph

Review in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Heng DuDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Guowei CheDepartment of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor microenvironment is closely related to tumor progression. Cancer-associated fibroblasts (CAFs) are specialized fibroblasts domesticated by cancer cells surrounding them. CAFs are one of the most important components in cancer microenvironment. CAFs extensively involved in tumor genesis, tumor invasion and metastasis. Compared to NFs, CAFs also have a different metabolism type. CAFs use glycolysis to produce lactate for cancer cells. That is, CAFs turn to a metabolism type named "reverse Warburg effect" to promote tumor progression. In the present study, we summarized that: (1) Characteristics and metabolic type of CAFs; (2) The research status of the metabolism of CAFs; (3) The potential mechanism of CAFs metabolism; (4) The relation between metabolic alteration in CAFs and lung cancer progression; (5) Relationship between CAFs metabolism and lung cancer prognosis and therapy.

Indexed as

Disease ProgressionFibroblastsHumansLung NeoplasmsPrognosis

Identifiers

PMID25248710
PMCPMC6000513
OpenAlexW2418360602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.