ArticleThe Plant cell2014
Arabidopsis DE-ETIOLATED1 represses photomorphogenesis by positively regulating phytochrome-interacting factors in the dark.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed, 139 citations in OpenAlex.
- A functional atlas of transposon-encoded products and their integration into host networks.Nature communications · 2026Article
- Light at the heart of time: How photoreceptors entrain the circadian clock.Plant communications · 2026Review
- PlantSetDelta: Mining regulatory features to enable interpretable gene set analysis in plants.Plant communications · 2026Article
- CUL3Science advances · 2026Article
- Light interacts with mechanical stress to regulate the seed-to-seedling transition.Stress biology · 2025Review
- Transcriptional dynamics and chromatin accessibility in the regulation of shade-responsive genes in Arabidopsis.Genome biology · 2025Article
- Threshold-dependent negative autoregulation of PIF4 gene expression optimizes growth and fitness in Arabidopsis.PLoS genetics · 2025Article
- Role of functional genes for seed vigor related traits through genome-wide association mapping in finger millet (Eleusine coracana L. Gaertn.).Scientific reports · 2025Article
- The lowdown on breakdown: Open questions in plant proteolysis.The Plant cell · 2024Review
- A circadian clock output functions independently of phyB to sustain daytime PIF3 degradation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- What is going on inside of phytochrome B photobodies?The Plant cell · 2024Review
- Light controls mesophyll-specific post-transcriptional splicing of photoregulatory genes by AtPRMT5.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Genome-wide identification and comprehensive analysis of the phytochrome-interacting factor (PIF) gene family in wheat.PloS one · 2024Article
- Article
- Light regulation of the biosynthesis of phenolics, terpenoids, and alkaloids in plants.Communications biology · 2023Review
- Light signaling as cellular integrator of multiple environmental cues in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Review
- MYB112 connects light and circadian clock signals to promote hypocotyl elongation in Arabidopsis.The Plant cell · 2023Article
- Review
- Functions of Plant Phytochrome Signaling Pathways in Adaptation to Diverse Stresses.International journal of molecular sciences · 2023Review
- The Role of Light Quality in Regulating Early Seedling Development.Plants (Basel, Switzerland) · 2023Review
17 more citing papers are in PubMed but not listed here.
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Arabidopsis thaliana seedlings undergo photomorphogenic development even in darkness when the function of DE-ETIOLATED1 (DET1), a repressor of photomorphogenesis, is disrupted. However, the mechanism by which DET1 represses photomorphogenesis remains unclear. Our results indicate that DET1 directly interacts with a group of transcription factors known as the phytochrome-interacting factors (PIFs). Furthermore, our results suggest that DET1 positively regulates PIF protein levels primarily by stabilizing PIF proteins in the dark. Genetic analysis showed that each pif single mutant could enhance the det1-1 phenotype, and ectopic expression of each PIF in det1-1 partially suppressed the det1-1 phenotype, based on hypocotyl elongation and cotyledon opening angles observed in darkness. Genomic analysis also revealed that DET1 may modulate the expression of light-regulated genes to mediate photomorphogenesis partially through PIFs. The observed interaction and regulation between DET1 and PIFs not only reveal how DET1 represses photomorphogenesis, but also suggest a possible mechanism by which two groups of photomorphogenic repressors, CONSTITUTIVE PHOTOMORPHOGENESIS/DET/FUSCA and PIFs, work in concert to repress photomorphogenesis in darkness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.