Evidence map›Paper›PMID 25248294›Full record

ArticleTrends in neurosciences2014

Formation of excitation-inhibition balance: inhibition listens and changes its tune.

Huizhong W Tao, Ya-tang Li, Li I Zhang

Abstract readComment
In one paragraph

Article in Trends in neurosciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Organizational Principles of the Primate Cerebral Cortex at the Single-Cell Level.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. PDE4 Inhibition Restores the Balance Between Excitation and Inhibition in VTA Dopamine Neurons Disrupted by Repeated In Vivo Cocaine Exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017
    Article
  18. Article
  19. Plasticity during motherhood: changes in excitatory and inhibitory layer 2/3 neurons in auditory cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Huizhong W TaoZilkha Neurogenetic Institute, Los Angeles, CA 90089, USA; Department of Cell and Neurobiology, Zilkha Neurogenetic Institute, Los Angeles, CA 90089, USA. Electronic address: htao@usc.edu.
Ya-tang LiZilkha Neurogenetic Institute, Los Angeles, CA 90089, USA.
Li I ZhangZilkha Neurogenetic Institute, Los Angeles, CA 90089, USA; Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA. Electronic address: liizhang@usc.edu.

Funding

Processing and transformation of visual signals in the superior colliculusR01EY019049 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TAO, HUIZHONG WHIT · 2008 to 2025
$9.2M
Thalamic Modulation of Auditory Cortical Processing via LPR01DC008983 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Li I Zhang · 2007 to 2026
$8.7M
NEI NIH HHS R01 EY019049NIDCD NIH HHS R01 DC008983NIDCD NIH HHS R01DC DC008983
6 · The paper itself

Abstract

Recently, Xue, Atallah, and Scanziani reported that excitation/inhibition ratios across cortical pyramidal neurons are equalized by activity-dependent modulations of parvalbumin-neuron mediated feedforward inhibition. Their results raise questions about the developmental formation of this excitation-inhibition balance and the potential activity-dependent synaptic plasticity rules that mediate this process.

Indexed as

AnimalsFemaleHumansMaleNeuronsVisual Cortex

Identifiers

PMID25248294
PMCPMC4189014

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.