Evidence map›Paper›PMID 25247685›Full record

ArticleMolecules (Basel, Switzerland)2014

Comparative studies on polyphenolic composition, antioxidant and antimicrobial activities of Schisandra chinensis leaves and fruits.

Andrei Mocan, Gianina Crișan, Laurian Vlase, Ovidiu Crișan, Dan Cristian Vodnar, Oana Raita, Ana-Maria Gheldiu, Anca Toiu, Radu Oprean, Ioan Tilea

Open access · goldAbstract readComparative Study
In one paragraph

Article in Molecules (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.

  1. Pooled it
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  6. Designing combinational herbal drugs based on target space analysis.BMC complementary medicine and therapies · 2024
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  8. Emergence of theMicrobiology spectrum · 2023
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  9. Review
  10. An analysis of the nutritional effects ofFrontiers in nutrition · 2023
    Review
  11. International journal of molecular sciences · 2022
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  13. Synthesis and biological characterization of low-calorieFood science and biotechnology · 2022
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  14. Article
  15. Article
  16. Antioxidant Effects ofAntioxidants (Basel, Switzerland) · 2021
    Review
  17. Antioxidants (Basel, Switzerland) · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Andrei MocanDepartment of Pharmaceutical Botany, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creangă Street, Cluj-Napoca 400010, Romania. mocan.andrei@umfcluj.ro.
Gianina CrișanDepartment of Pharmaceutical Botany, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creangă Street, Cluj-Napoca 400010, Romania. gcrisan@umfcluj.ro.
Laurian VlaseDepartment of Pharmaceutical Technology and Biopharmaceutics, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creangă Street, Cluj-Napoca 400010, Romania. laurian.vlase@umfcluj.ro.
Ovidiu CrișanDepartment of Organic Chemistry, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creangă Street, Cluj- Napoca 400010, Romania. ocrisan@umfcluj.ro.
Dan Cristian VodnarDepartment of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine, 3-5 Manăştur Street, Cluj-Napoca 400372, Romania. dan.vodnar@usamvcluj.ro.
Oana RaitaDepartment of Physics of Nanostructured Materials, National Institute for Research and Development of Isotopic and Molecular Technologies 65-103, Donath Street, Cluj-Napoca 400010, Romania. oana.raita@itim-cj.ro.
Ana-Maria GheldiuDepartment of Pharmaceutical Technology and Biopharmaceutics, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creangă Street, Cluj-Napoca 400010, Romania. Gheldiu.Ana@umfcluj.ro.
Anca ToiuDepartment of Pharmacognosy, Iuliu Hațieganu University of Medicine and Pharmacy, 12 I. Creangă Street, Cluj-Napoca 400010, Romania. atoiu@umfcluj.ro.
Radu OpreanDepartment of Analytical Chemistry and Instrumental Analysis, Iuliu Hațieganu University of Medicine and Pharmacy, 4 L. Pasteur Street, Cluj-Napoca 400010, Romania. roprean@umfcluj.ro.
Ioan TileaFamily Medicine, Department M3 Clinical Sciences Internal Medicine, University of Medicine and Pharmacy, 38 G. Marinescu Street, Târgu Mures 540139, Romania. ioan.tilea@umftgm.ro.
Iuliu Hațieganu University of Medicine and Pharmacy · RONational Institute for Research and Development of Isotopic and Molecular Technologies · ROUniversitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș · ROUniversity of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this paper was to evaluate the antioxidant and antimicrobial activities and the polyphenolic content of Schisandra chinensis (Turcz.) Baill. leaves and fruits. The leaves are an important source of flavonoids (35.10 ± 1.23 mg RE/g plant material). Qualitative and quantitative analyses of the polyphenolic compounds were achieved using a HPLC-UV-MS method. The main flavonoid from the leaves was isoquercitrin (2486.18 ± 5.72 μg/g plant material), followed by quercitrin (1645.14 ± 2.12 μg/g plant material). Regarding the fruit composition, the dominant compound there was rutin (13.02 ± 0.21 μg/g plant material), but comparing with the leaves, fruits can be considered a poor source of phenolic compounds. The antioxidant activity was evaluated by DPPH, TEAC, hemoglobin ascorbate peroxidase activity inhibition (HAPX), inhibition of lipid peroxidation catalyzed by cytochrome c and EPR spectroscopic assays, revealing a better antioxidant activity for the S. chinensis leaves extract. In the antimicrobial assay, S. chinensis leaves extract showed efficient activities against the targeted bacteria, being more active than the fruits extract. The results suggest the leaves of S. chinensis as a valuable source of antioxidant compounds with significant antioxidant activity.

Indexed as

Anti-Infective AgentsAntioxidantsChromatography, High Pressure LiquidElectron Spin Resonance SpectroscopyMass SpectrometryMicrobial Sensitivity TestsPlant LeavesPolyphenolsSchisandraSpectrophotometry, UltravioletAnti-Infective AgentsAntioxidantsPolyphenols

Identifiers

PMID25247685
PMCPMC6270802
OpenAlexW1984343434

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.