Evidence map›Paper›PMID 25247192›Full record

Trial reportBioMed research international2014

Radiofrequency thermoablation of HCC larger than 3 cm and less than 5 cm proximal to the gallbladder without gallbladder isolation: a single center experience.

Antonio Orlacchio, Fabrizio Chegai, Costantino Del Giudice, Mariangela Massaccesi, Elisa Costanzo, Elena Di Caprera, Giovanni Simonetti

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Antonio OrlacchioDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.
Fabrizio ChegaiDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0001-8736-6475
Costantino Del GiudiceDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0002-9383-122X
Mariangela MassaccesiDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.
Elisa CostanzoDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.
Elena Di CapreraDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.ORCID 0000-0002-5495-1624
Giovanni SimonettiDepartment of Diagnostic and Molecular Imaging, Radiation Therapy and Interventional Radiology, University Hospital "Policlinico Tor Vergata," Viale Oxford 81, 00133 Rome, Italy.
Policlinico Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiofrequency ablation (RFA) is an effective minimally invasive treatment for nonsurgical hepatocellular carcinoma (HCC), but ablation of tumors close to the gallbladder could be associated with several complications. We report our experience on the treatment of HCC close to the gallbladder with RFA. Eight RFA procedures were performed in eight patients with HCC larger than 3 cm and less than 5 cm close to the gallbladder. In all cases, a percutaneous approach was used. There were no major complications. Only in two patients a minimal wall thickening of the gallbladder was observed. Contrast enhanced computed tomography carried out after 30 days from the first procedure showed complete necrosis in seven patients (87%). Only one patient had local recurrence at 11 months of followup. Although limited, our experience suggests that, after careful preprocedural planning, in experienced hands and with appropriate technology, percutaneous RFA could be safely performed even for lesions larger than 3 cm located in close adjacency to the gallbladder.

Indexed as

CholecystographyAgedCarcinoma, HepatocellularCatheter AblationFemaleGallbladderHepatectomyHumansLiver NeoplasmsMaleMiddle AgedOrgan Sparing TreatmentsTreatment Outcome

Identifiers

PMID25247192
PMCPMC4163369
OpenAlexW2100385973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.