ReviewAnnals of surgical treatment and research2014
The clinical features and optimal treatment of anorectal malignant melanoma.
Review in Annals of surgical treatment and research, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Comparison of survival outcomes between local excision and radical resection in patients with rectal mucosal melanoma.World journal of surgical oncology · 2026Article
- Detection and surgical intervention in anorectal malignant melanoma: a case report.Journal of medical case reports · 2026Article
- Consider the unexpected! An overlooked, elusive, rare but dramatic diagnosis: anorectal melanoma.Updates in surgery · 2025Article
- Anorectal Malignant Melanoma: Diagnostic Pitfalls and Prognostic Insights from a Single-Center Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Anal melanoma: a clinical challenge without therapeutic consensus.Journal of surgical case reports · 2025Article
- Case Report: Surgery combined with targeted therapy for metastatic anorectal malignant mucosal melanoma.Frontiers in oncology · 2025Article
- Article
- Primary anorectal amelanotic melanoma with liver, lungs and lymph nodal metastases.BMJ case reports · 2023Article
- Anorectal and Genital Mucosal Melanoma: Diagnostic Challenges, Current Knowledge and Therapeutic Opportunities of Rare Melanomas.Biomedicines · 2022Review
- Difficulties in diagnosing anorectal melanoma: A case report and review of the literature.World journal of clinical cases · 2021Article
- Anorectal Melanoma Misdiagnosed as Hemorrhoids: A Case Report and Review of the Literature.The Journal of clinical and aesthetic dermatology · 2021Article
- Presentation, Management, and Prognosis of Primary Gastrointestinal Melanoma: A Population-Based Study.The Journal of surgical research · 2021Article
- Distribution pattern of tumor infiltrating lymphocytes and tumor microenvironment composition as prognostic indicators in anorectal malignant melanoma.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2021Article
- Patterns of Care and Survival Outcomes in the Treatment of Anal Melanoma.Journal of gastrointestinal cancer · 2020Article
- Primary anorectal malignant melanoma: A case report.Medicine · 2020Article
- A case report of anorectal malignant melanoma in the transitional zone.International journal of surgery case reports · 2020Article
- Endoscopic submucosal dissection as excisional biopsy for anorectal malignant melanoma: A case report.World journal of clinical cases · 2019Article
- Amelanocytic anorectal malignant melanoma-Case report.International journal of surgery case reports · 2019Article
- Notch1 signaling in melanoma cells promoted tumor-induced immunosuppression via upregulation of TGF-β1.Journal of experimental & clinical cancer research : CR · 2018Article
- Black Is the New Black: Prolapsing Primary Anorectal Melanoma.Digestive diseases and sciences · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anorectal malignant melanoma (AMM) is a very rare and aggressive disease. The purpose of this article is to review the clinical features of AMM, to understand treatment options, and optimal therapy by reviewing pertinent literature. Traditionally an abdominoperineal resection (APR) sacrificing the anal sphincter has been performed for radical resection of cancer, but recently, wide excision of AMM is attempted since quality of life after surgery is an important issue. Some authors reported that there was no difference in five-year survival between the patient who underwent an APR and wide excision. The goal of both APR and wide excision was to improve survival with R0 resection. Adjuvant chemoradiation therapy can be performed to achieve an R0 resection. AMM shows very poor prognosis. At this time, research on AMM is insufficient to suggest a treatment guideline. Thus, treatment options, and a therapeutic method should be selected carefully.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.