Evidence map›Paper›PMID 25247135›Full record

ReviewBeilstein journal of nanotechnology2014

Current state of laser synthesis of metal and alloy nanoparticles as ligand-free reference materials for nano-toxicological assays.

Christoph Rehbock, Jurij Jakobi, Lisa Gamrad, Selina van der Meer, Daniela Tiedemann, Ulrike Taylor, Wilfried Kues, Detlef Rath, Stephan Barcikowski

Abstract readReview
In one paragraph

Review in Beilstein journal of nanotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Laser Ablation of NiFeNanomaterials (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christoph RehbockTechnical Chemistry I and Center for Nanointegration Duisburg-Essen (CENIDE), Universitaetsstr. 7, 45141 Essen, Germany.
Jurij JakobiTechnical Chemistry I and Center for Nanointegration Duisburg-Essen (CENIDE), Universitaetsstr. 7, 45141 Essen, Germany.
Lisa GamradTechnical Chemistry I and Center for Nanointegration Duisburg-Essen (CENIDE), Universitaetsstr. 7, 45141 Essen, Germany.
Selina van der MeerTechnical Chemistry I and Center for Nanointegration Duisburg-Essen (CENIDE), Universitaetsstr. 7, 45141 Essen, Germany.
Daniela TiedemannInstitute for Farm Animal Genetics, Friedrich-Loeffler-Institut, Höltystr. 10, 31535 Neustadt, Germany.
Ulrike TaylorInstitute for Farm Animal Genetics, Friedrich-Loeffler-Institut, Höltystr. 10, 31535 Neustadt, Germany.
Wilfried KuesInstitute for Farm Animal Genetics, Friedrich-Loeffler-Institut, Höltystr. 10, 31535 Neustadt, Germany.
Detlef RathInstitute for Farm Animal Genetics, Friedrich-Loeffler-Institut, Höltystr. 10, 31535 Neustadt, Germany.
Stephan BarcikowskiTechnical Chemistry I and Center for Nanointegration Duisburg-Essen (CENIDE), Universitaetsstr. 7, 45141 Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the abundance of nanomaterials in medical devices and everyday products, toxicological effects related to nanoparticles released from these materials, e.g., by mechanical wear, are a growing matter of concern. Unfortunately, appropriate nanoparticles required for systematic toxicological evaluation of these materials are still lacking. Here, the ubiquitous presence of surface ligands, remaining from chemical synthesis are a major drawback as these organic residues may cause cross-contaminations in toxicological studies. Nanoparticles synthesized by pulsed laser ablation in liquid are a promising alternative as this synthesis route provides totally ligand-free nanoparticles. The first part of this article reviews recent methods that allow the size control of laser-fabricated nanoparticles, focusing on laser post irradiation, delayed bioconjugation and in situ size quenching by low salinity electrolytes. Subsequent or parallel applications of these methods enable precise tuning of the particle diameters in a regime from 4-400 nm without utilization of any artificial surface ligands. The second paragraph of this article highlights the recent progress concerning the synthesis of composition controlled alloy nanoparticles by laser ablation in liquids. Here, binary and ternary alloy nanoparticles with totally homogeneous elemental distribution could be fabricated and the composition of these particles closely resembled bulk implant material. Finally, the model AuAg was used to systematically evaluate composition related toxicological effects of alloy nanoparticles. Here Ag(+) ion release is identified as the most probable mechanism of toxicity when recent toxicological studies with gametes, mammalian cells and bacteria are considered.

Indexed as

albumingold-silverimplant alloylaser ablationnickel-titaniumsize controlwear debris

Identifiers

PMID25247135
PMCPMC4168911

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.