Evidence map›Paper›PMID 25247131›Full record

ReviewBeilstein journal of nanotechnology2014

In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far?

Moritz Nazarenus, Qian Zhang, Mahmoud G Soliman, Pablo Del Pino, Beatriz Pelaz, Susana Carregal-Romero, Joanna Rejman, Barbara Rothen-Rutishauser, Martin J D Clift, Reinhard Zellner and 4 more

Abstract readReview
In one paragraph

Review in Beilstein journal of nanotechnology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Moritz NazarenusFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany.
Qian ZhangFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany.
Mahmoud G SolimanFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany.
Pablo Del PinoCIC Biomagune, Paseo Miramón 182, 20009 San Sebastian, Spain.
Beatriz PelazFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany.
Susana Carregal-RomeroFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany.
Joanna RejmanFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany.
Barbara Rothen-RutishauserBioNanomaterials, Adolphe Merkle Institute, University of Fribourg, Route de L'ancienne Papeterie CP 209, Marly 1, 1723, Fribourg, Switzerland.
Martin J D CliftBioNanomaterials, Adolphe Merkle Institute, University of Fribourg, Route de L'ancienne Papeterie CP 209, Marly 1, 1723, Fribourg, Switzerland.
Reinhard ZellnerInstitute of Physical Chemistry, University of Duisburg-Essen, Universitätsstraße 5, 45141 Essen, Germany.
G Ulrich NienhausInstitute of Applied Physics and Institute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), Wolfgang-Gaede-Straße 1, 76131 Karlsruhe, Germany ; Department of Physics, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, IL 61801, USA.
James B DelehantyCenter for Bio/Molecular Science & Engineering, Code 6900, U.S. Naval Research Laboratory, 4555 Overlook Avenue Southwest, Washington D.C., 20375, USA.
Igor L MedintzCenter for Bio/Molecular Science & Engineering, Code 6900, U.S. Naval Research Laboratory, 4555 Overlook Avenue Southwest, Washington D.C., 20375, USA.
Wolfgang J ParakFachbereich Physik, Philipps-Universität Marburg, Renthof 7, 35037 Marburg, Germany ; CIC Biomagune, Paseo Miramón 182, 20009 San Sebastian, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interfacing of colloidal nanoparticles with mammalian cells is now well into its second decade. In this review our goal is to highlight the more generally accepted concepts that we have gleaned from nearly twenty years of research. While details of these complex interactions strongly depend, amongst others, upon the specific properties of the nanoparticles used, the cell type, and their environmental conditions, a number of fundamental principles exist, which are outlined in this review.

Indexed as

colloidal stabilityintracellular particle distributionnanoparticlesprotein coronatoxicity of nanoparticles

Identifiers

PMID25247131
PMCPMC4168913

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.