Evidence map›Paper›PMID 25246697›Full record

ArticleThe American journal of tropical medicine and hygiene2014

Quantitative evaluation of a handheld light microscope for field diagnosis of soil-transmitted helminth infection.

Isaac I Bogoch, Jason R Andrews, Benjamin Speich, Shaali M Ame, Said M Ali, J Russell Stothard, Jürg Utzinger, Jennifer Keiser

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Isaac I BogochDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom isaac.bogoch@uhn.ca.
Jason R AndrewsDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Benjamin SpeichDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Shaali M AmeDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Said M AliDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
J Russell StothardDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Jürg UtzingerDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Jennifer KeiserDivisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada; Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California; Department of Medical Parasitology and Infection Biology, and Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland; Public Health Laboratory Ivo de Carneri, Chake, Chake, Pemba Island, Tanzania; Department of Parasitology, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
Swiss Tropical and Public Health Institute · CH

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
FIC NIH HHS D43 TW010540
6 · The paper itself

Abstract

We evaluated the Newton Nm1, a commercially available handheld light microscope and compared it with conventional light microscopy for the diagnosis of soil-transmitted helminth infections. A total of 91 Kato-Katz thick smears were examined by experienced microscopists and helminth eggs were counted and expressed as eggs per gram of stool (EPG). Mean egg counts were significantly higher with the conventional light microscope (5,190 EPG versus 2,386 EPG for Ascaris lumbricoides; 826 versus 456 for Trichuris trichiura; both P < 0.05). Using regression coefficients and accounting for intensity of infection, we found that the agreement between the two devices was excellent for both species (κ = 0.90, 95% confidence interval = 0.82-0.99 for A. lumbricoides and κ = 0.96, 95% CI = 0.91-1.00 for T. trichiura). The Newton Nm1 microscope may be a useful tool for the detection and quantification of soil-transmitted helminth infection in clinical, epidemiologic, and public health settings.

Indexed as

AnimalsHelminthiasisHumansMicroscopyParasite Egg CountSoilSoil

Identifiers

PMID25246697
PMCPMC4257635
OpenAlexW2149122058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.