Evidence map›Paper›PMID 25246696›Full record

ArticleThe American journal of tropical medicine and hygiene2014

High Schistosoma mansoni disease burden in a rural district of western Zambia.

Mable M Mutengo, James C L Mwansa, Takafira Mduluza, Sandie Sianongo, James Chipeta

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Prevalence and Molecular Identification ofTropical medicine and infectious disease · 2022
    Article
  10. Article
  11. Schistosomiasis with a Focus on Africa.Tropical medicine and infectious disease · 2021
    Review
  12. Article
  13. Observational
  14. In vitro Effects ofResearch and reports in tropical medicine · 2020
    Article
  15. Article
  16. Review
  17. Low IL-6, IL-10, and TNF-Journal of parasitology research · 2018
    Article
  18. Article
  19. Prevalence and intensity ofTropical parasitology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mable M MutengoDepartment of Pathology and Microbiology, University of Zambia School of Medicine, Lusaka, Zambia; Department of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia; Department of Biochemistry, University of Zimbabwe, Harare, Zimbabwe; Department of Pediatrics and Child Health, University of Zambia School of Medicine, Lusaka, Zambia.
James C L MwansaDepartment of Pathology and Microbiology, University of Zambia School of Medicine, Lusaka, Zambia; Department of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia; Department of Biochemistry, University of Zimbabwe, Harare, Zimbabwe; Department of Pediatrics and Child Health, University of Zambia School of Medicine, Lusaka, Zambia.
Takafira MduluzaDepartment of Pathology and Microbiology, University of Zambia School of Medicine, Lusaka, Zambia; Department of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia; Department of Biochemistry, University of Zimbabwe, Harare, Zimbabwe; Department of Pediatrics and Child Health, University of Zambia School of Medicine, Lusaka, Zambia.
Sandie SianongoDepartment of Pathology and Microbiology, University of Zambia School of Medicine, Lusaka, Zambia; Department of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia; Department of Biochemistry, University of Zimbabwe, Harare, Zimbabwe; Department of Pediatrics and Child Health, University of Zambia School of Medicine, Lusaka, Zambia.
James ChipetaDepartment of Pathology and Microbiology, University of Zambia School of Medicine, Lusaka, Zambia; Department of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia; Department of Biochemistry, University of Zimbabwe, Harare, Zimbabwe; Department of Pediatrics and Child Health, University of Zambia School of Medicine, Lusaka, Zambia Jameschipeta@smuth-mru.org.zm.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Schistosoma mansoni disease is endemic in most parts of rural Zambia, and associated complications are common. We conducted a cross-sectional study among 754 people in rural communities of Kaoma District, western Zambia to determine the burden of S. mansoni infection and associated morbidity. Parasitology and ultrasonography assessments were conducted on consenting participants. The overall prevalence of S. mansoni infection and geometric mean egg count (GMEC) were 42.4% (304) and 86.6 eggs per gram (95% confidence interval = 75.6-99.6), respectively. Prevalence was highest in the age group of 15-19 years old (adjusted prevalence ratio = 1.70, P = 0.017). S. mansoni-related portal fibrosis was detected in 26% of the participants screened. Participants above 39 years old were 2.93 times more likely to have fibrosis than the 7-9 years old age group (P = 0.004). The study highlights the high burden of S. mansoni disease in this area and calls for immediate interventions to avert complications associated with the disease.

Indexed as

Cost of IllnessAdolescentAdultAge FactorsAnimalsChildCross-Sectional StudiesFemaleFibrosisHumansLogistic ModelsMaleMiddle AgedMorbidityMultivariate AnalysisParasite Egg Count

Identifiers

PMID25246696
PMCPMC4228894

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.