ArticleProceedings of the National Academy of Sciences of the United States of America2014
FBH1 affects warm temperature responses in the Arabidopsis circadian clock.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Dissecting usuranme biquitin-mediated circadian clock regulation in Arabidopsis via high-throughput yeast screens.Journal of experimental botany · 2025Article
- Temperature compensation of the Arabidopsis circadian clock.Npj biological timing and sleep · 2025Review
- Transcriptional activation and repression in the plant circadian clock: Revisiting core oscillator feedback loops and output pathways.Plant communications · 2025Review
- Suppressed DNA repair capacity in flight attendants after air travel.Scientific reports · 2025Article
- The clock-associated LUX ARRHYTHMO regulates high-affinity nitrate transport in Arabidopsis roots.The Plant journal : for cell and molecular biology · 2024Article
- The overexpression of the switchgrass (Panicum virgatum L.) genes PvTOC1-N or PvLHY-K affects circadian rhythm and hormone metabolism in transgenic Arabidopsis seedlings.Biotechnology for biofuels and bioproducts · 2024Article
- The interplay between the circadian clock and abiotic stress responses mediated by ABF3 and CCA1/LHY.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- The Roles of Circadian Clock Genes in Plant Temperature Stress Responses.International journal of molecular sciences · 2024Review
- C4 Phosphoenolpyruvate Carboxylase: Evolution and transcriptional regulation.Genetics and molecular biology · 2024Article
- Environmental F actors coordinate circadian clock function and rhythm to regulate plant development.Plant signaling & behavior · 2023Review
- Molecular insights into mechanisms underlying thermo-tolerance in tomato.Frontiers in plant science · 2022Review
- Clock-Controlled and Cold-InducedFrontiers in plant science · 2022Article
- A mobile ELF4 delivers circadian temperature information from shoots to roots.Nature plants · 2020Article
- Ubiquitin carboxyl-terminal hydrolases are required for period maintenance of the circadian clock at high temperature in Arabidopsis.Scientific reports · 2019Article
- Enhanced Maps of Transcription Factor Binding Sites Improve Regulatory Networks Learned from Accessible Chromatin Data.Plant physiology · 2019Article
- ABI5-BINDING PROTEIN2 Coordinates CONSTANS to Delay Flowering by Recruiting the Transcriptional Corepressor TPR2.Plant physiology · 2019Article
- Arabidopsis JMJD5/JMJ30 Acts Independently of LUX ARRHYTHMO Within the Plant Circadian Clock to Enable Temperature Compensation.Frontiers in plant science · 2019Article
- Ambient Temperature-Responsive Mechanisms Coordinate Regulation of Flowering Time.International journal of molecular sciences · 2018Review
- The FBH family of bHLH transcription factors controls ACC synthase expression in sugarcane.Journal of experimental botany · 2018Article
- Rapid transcriptional and metabolic regulation of the deacclimation process in cold acclimated Arabidopsis thaliana.BMC genomics · 2017Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
In Arabidopsis, the circadian clock allows the plant to coordinate daily external signals with internal processes, conferring enhanced fitness and growth vigor. Although external cues such as temperature can entrain the clock, an important feature of the clock is the ability to maintain a relatively constant period over a range of physiological temperatures; this ability is referred to as "temperature compensation." However, how temperature actually is perceived and integrated into the clock molecular circuitry remains largely unknown. In an effort to identify additional regulators of the circadian clock, including putative components that could modulate the clock response to changes in environmental signals, we identified in a previous large-scale screen a transcription factor that interacts with and regulates the promoter activity of a core clock gene. In this report, we characterized this transcription factor, flowering basic helix-loop-helix 1 (FBH1) that binds in vivo to the promoter of the key clock gene circadian clock-associated 1 (CCA1) and regulates its expression. We found that upon temperature changes, overexpression of FBH1 alters the pace of CCA1 expression by causing a period shortening and thus preventing the clock from buffering against this change in temperature. Furthermore, as is consistent with the current mechanistic model of feedback loops observed in the clock regulatory network, we also determined that CCA1 binds in vivo to the FBH1 promoter and regulates its expression. Together these results establish a role for FBH1 as a transcriptional modulator of warm temperature signals and clock responses in Arabidopsis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.