Evidence map›Paper›PMID 25246424›Full record

ArticleInternational journal of STD & AIDS2015

Disparities in herpes simplex virus type 2 infection between black and white men who have sex with men in Atlanta, GA.

Netochukwu Okafor, Eli S Rosenberg, Nicole Luisi, Travis Sanchez, Carlos del Rio, Patrick S Sullivan, Colleen F Kelley

Open access · greenAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Netochukwu OkaforDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Eli S RosenbergDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Nicole LuisiDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Travis SanchezDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Carlos del RioDepartment of Global Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA Division of Infectious Diseases, Department of Medicine, Emory University, Atlanta, GA, USA.
Patrick S SullivanDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Colleen F KelleyDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA Division of Infectious Diseases, Department of Medicine, Emory University, Atlanta, GA, USA colleen.kelley@emory.edu.
Emory University · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Carlos del Rio · 2002 to 2026
$74.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Explaining Differences in HIV Prevalence and Incidence in Black and White MSMR01MH085600 · NIMH · EMORY UNIVERSITY · PI SULLIVAN, PATRICK SEAN · 2009 to 2013
$2.9M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
Defining the rectal mucosa in MSM at risk of HIV infectionK23AI108335 · NIAID · EMORY UNIVERSITY · PI KELLEY, COLLEEN F · 2013 to 2017
$855k
NCATS NIH HHS KL2 TR000455NCATS NIH HHS KL2TR000455NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1TR000454NCRR NIH HHS P51RR169NIAID NIH HHS K23 AI108335NIAID NIH HHS K23AI108335NIAID NIH HHS P30 AI050409NIAID NIH HHS P30AI050409NIH HHS P51 OD011107NIH HHS P51OD11107NIMH NIH HHS R01 MH085600NIMH NIH HHS R01MH085600
6 · The paper itself

Abstract

HIV disproportionately affects black men who have sex with men, and herpes simplex virus type 2 is known to increase acquisition of HIV. However, data on racial disparities in herpes simplex virus type 2 prevalence and risk factors are limited among men who have sex with men in the United States. InvolveMENt was a cohort study of black and white HIV-negative men who have sex with men in Atlanta, GA. Univariate and multivariate cross-sectional associations with herpes simplex virus type 2 seroprevalence were assessed among 455 HIV-negative men who have sex with men for demographic, behavioural and social determinant risk factors using logistic regression. Seroprevalence of herpes simplex virus type 2 was 23% (48/211) for black and 16% (38/244) for white men who have sex with men (p = 0.05). Education, poverty, drug/alcohol use, incarceration, circumcision, unprotected anal intercourse, and condom use were not associated with herpes simplex virus type 2. In multivariate analyses, black race for those ≤25 years, but not >25 years, and number of sexual partners were significantly associated. Young black men who have sex with men are disproportionately affected by herpes simplex virus type 2, which may contribute to disparities in HIV acquisition. An extensive assessment of risk factors did not explain this disparity in herpes simplex virus type 2 infection suggesting differences in susceptibility or partner characteristics.

Indexed as

Homosexuality, MaleAdolescentAdultBlack or African AmericanBlack PeopleCross-Sectional StudiesHerpes GenitalisHerpes SimplexHerpesvirus 2, HumanHIV InfectionsHumansLogistic ModelsLongitudinal StudiesMaleMultivariate AnalysisRisk FactorsAIDSdisparitiesherpes simplex virus type 2HIVHSV2men who have sex with menseroprevalenceSexually transmitted infectionsUSA

Identifiers

PMID25246424
PMCPMC4430438
OpenAlexW2107423545

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.