ArticleG3 (Bethesda, Md.)2014
Population- and sex-biased gene expression in the excretion organs of Drosophila melanogaster.
Article in G3 (Bethesda, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed.
- Conservation and divergence of sex-biased gene expression across 50 million years of Drosophila evolution.Molecular biology and evolution · 2026Article
- Expression of De Novo Open Reading Frames in Natural Populations of Drosophila melanogaster.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2025Article
- Evolutionary Analysis of Sex-Biased Gene Suggests Functional Conservation of Lifespan-Related Genes in Insecta.Biology · 2025Article
- Genetic, Environmental, and Stochastic Components of Lifespan Variability: TheInternational journal of molecular sciences · 2024Review
- Impact of Heat Stress on Transposable Element Expression and Derived Small RNAs in Drosophila subobscura.Genome biology and evolution · 2023Article
- Nonlinear expression patterns and multiple shifts in gene network interactions underlie robust phenotypic change in Drosophila melanogaster selected for night sleep duration.PLoS computational biology · 2023Article
- Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster.Genetics · 2023Article
- Dynamics and stage-specificity of between-population gene expression divergence in the Drosophila melanogaster larval fat body.PLoS genetics · 2023Article
- RNA-Seq Analysis Reveals Expression Regulatory Divergence of W-Linked Genes between Two Contrasting Chicken Breeds.Animals : an open access journal from MDPI · 2022Article
- Gene expression profiles in Malpighian tubules of the vector leafhopper Psammotettix striatus (L.) revealed regional functional diversity and heterogeneity.BMC genomics · 2022Article
- Sexual Antagonism, Temporally Fluctuating Selection, and Variable Dominance Affect a Regulatory Polymorphism in Drosophila melanogaster.Molecular biology and evolution · 2021Article
- Parallel and population-specific gene regulatory evolution in cold-adapted fly populations.Genetics · 2021Article
- Identification of Genes Contributing to a Long Circadian Period inJournal of biological rhythms · 2021Article
- Article
- The α/β-hydrolase domain-containing 4- and 5-related phospholipase Pummelig controls energy storage inJournal of lipid research · 2019Article
- Pleiotropy Modulates the Efficacy of Selection in Drosophila melanogaster.Molecular biology and evolution · 2019Article
- Population Genetic and Functional Analysis of aGenes · 2019Article
- Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster.Behavior genetics · 2019Article
- Transcriptome Analysis Reveals Candidate Genes for Cold Tolerance in Drosophila ananassae.Genes · 2018Article
- Genetic constraints on microevolutionary divergence of sex-biased gene expression.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Within species, levels of gene expression typically vary greatly between tissues, sexes, individuals, and populations. To investigate gene expression variation between sexes and populations in a single somatic tissue, we performed a quantitative analysis of the Malpighian tubule transcriptome in adult males and females of Drosophila melanogaster derived from two distinct populations (one from sub-Saharan Africa and one from northern Europe). We identified 2308 genes that differed in expression between the sexes and 2474 genes that differed in expression between populations at a false discovery rate of 5%. We also identified more than 1000 genes that showed a sex-by-population interaction in their expression. The genes that differed in expression between sexes showed enrichment for a wide variety of functions, although only 55% of them overlapped with sex-biased genes identified in whole-fly studies. The genes expressed differentially between populations included several that were previously implicated in adaptive regulatory evolution, an excess of cytochrome P450 genes, and many genes that were not detected in previous studies of whole flies. Our results demonstrate that there is abundant intraspecific gene expression variation within in a single, somatic tissue and uncover new candidates for adaptive regulatory evolution between populations.
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