Evidence map›Paper›PMID 25245965›Full record

ReviewThe Surgical clinics of North America2014

Melanoma vaccines: mixed past, promising future.

Junko Ozao-Choy, Delphine J Lee, Mark B Faries

Abstract readReview
In one paragraph

Review in The Surgical clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2025
    Trial
  2. Immunotherapy and delivery systems for melanoma.Human vaccines & immunotherapeutics · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Immunotherapy of Melanoma: Facts and Hopes.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Advances in immunotherapy for melanoma management.Human vaccines & immunotherapeutics · 2016
    Review
  19. Nanomaterial-Based Vaccine Adjuvants.Journal of materials chemistry. B · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Junko Ozao-ChoyJohn Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
Delphine J LeeJohn Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA.
Mark B FariesJohn Wayne Cancer Institute, 2200 Santa Monica Boulevard, Santa Monica, CA 90404, USA. Electronic address: mark.faries@jwci.org.

Funding

SURGICAL ONCOLOGY WITH COMBINATION THERMO-CHEMOTHERAPYP01CA029605 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOON, DAVE S B · 1985 to 2013
$75.2M
NCI NIH HHS P01 CA029605NCI NIH HHS P01 CA29605
6 · The paper itself

Abstract

Cancer vaccines were one of the earliest forms of immunotherapy to be investigated. Past attempts to vaccinate against cancer, including melanoma, have mixed results, showing the complexity of what was believed to be a simple concept. However, several recent successes and the combination of improved knowledge of tumor immunology and the advent of new immunomodulators make vaccination a promising strategy for the future.

Indexed as

Adjuvants, ImmunologicAntigens, NeoplasmCancer VaccinesForecastingGangliosidesHumansImmunologic FactorsImmunotherapyMelanomaMulticenter Studies as TopicRandomized Controlled Trials as TopicSkin NeoplasmsVaccines, SubunitAdjuvants, ImmunologicAntigens, NeoplasmCancer VaccinesGangliosidesImmunologic FactorsVaccines, SubunitAdjuvantImmunomodulatorImmunotherapyMelanomaVaccine

Identifiers

PMID25245965
PMCPMC4173123

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.