Evidence map›Paper›PMID 25245815›Full record

ArticleBMC medical imaging2014

Interactive neonatal gastrointestinal magnetic resonance imaging using fruit juice as an oral contrast media.

Owen J Arthurs, Martin J Graves, Andrea D Edwards, Ilse Joubert, Pat A K Set, David J Lomas

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Owen J ArthursDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK. owen.arthurs@gosh.nhs.uk.
Martin J Graves
Andrea D Edwards
Ilse Joubert
Pat A K Set
David J Lomas
Cambridge University Hospitals NHS Foundation Trust · GBUniversity College London · GB

Funding

Medical Research Council G0800411
6 · The paper itself

Abstract

backgroundThe objective was to evaluate the use of fruit juice with an interactive inversion recovery (IR) MR pulse sequence to visualise the gastrointestinal tract.

methodsWe investigated the relaxation properties of 12 different natural fruit juices in vitro, to identify which could be used as oral contrast. We then describe our initial experience using an interactive MR pulse sequence to allow optimal visualisation after administering pineapple juice orally, and suppressing pre-existing bowel fluid contents, with variable TI in three adult and one child volunteer.

resultsPineapple juice (PJ) had both the shortest T1 (243 ms) and shortest T2 (48 ms) of the fruit juices tested. Optimal signal differentiation between pre-existing bowel contents and oral PJ administration was obtained with TIs of between 900 and 1100 ms.

conclusionThe use of an inversion recovery preparation allowed long T1 pre-existing bowel contents to be suppressed whilst the short T1 of fruit juice acts as a positive contrast medium. Pineapple juice could be used as oral contrast agent for neonatal gastrointestinal magnetic resonance imaging.

Indexed as

Administration, OralAdultAnanasContrast MediaFruitGastrointestinal TractHumansInfant, NewbornMagnetic Resonance ImagingMalePhantoms, ImagingPlant ExtractsRadiographyContrast MediaPlant Extracts

Identifiers

PMID25245815
PMCPMC4186814
OpenAlexW1999692667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.