Evidence map›Paper›PMID 25245501›Full record

ArticleChild abuse & neglect2014

Child maltreatment and blood pressure in young adulthood.

Holly C Gooding, Carly Milliren, Katie A McLaughlin, Tracy K Richmond, Sabra L Katz-Wise, Janet Rich-Edwards, S Bryn Austin

Abstract read
In one paragraph

Article in Child abuse & neglect, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  13. Childhood Maltreatment and Health Impact: The Examples of Cardiovascular Disease and Type 2 Diabetes Mellitus in Adults.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Holly C GoodingBoston Children's Hospital Division of Adolescent and Young Adult Medicine, 300 Longwood Avenue, Boston, MA 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
Carly MillirenClinical Research Center, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA.
Katie A McLaughlinDepartment of Psychology, University of Washington, 119A Guthrie Hall, UW Box 351525, Seattle, WA, USA.
Tracy K RichmondBoston Children's Hospital Division of Adolescent and Young Adult Medicine, 300 Longwood Avenue, Boston, MA 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
Sabra L Katz-WiseBoston Children's Hospital Division of Adolescent and Young Adult Medicine, 300 Longwood Avenue, Boston, MA 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA.
Janet Rich-EdwardsDepartment of Medicine, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
S Bryn AustinBoston Children's Hospital Division of Adolescent and Young Adult Medicine, 300 Longwood Avenue, Boston, MA 02115, USA; Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA; Department of Social and Behavioral Sciences, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
Boston Children's Hospital · USHarvard University · USUniversity of Washington · US

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
Child adversity and the developmental epidemiology of mood and anxiety disorders.K01MH092526 · NIMH · UNIVERSITY OF WASHINGTON · PI MCLAUGHLIN, KATIE · 2011 to 2015
$846k
NHLBI NIH HHS L30 HL115615NICHD NIH HHS P01 HD031921NICHD NIH HHS P01-HD31921NIMH NIH HHS K01 MH092526
6 · The paper itself

Abstract

Adverse childhood experiences are associated with hypertension in older adults. This study assessed whether an association between child maltreatment and blood pressure is detectable in young adults and whether any association differs by sex or is modified by genetic polymorphisms known to be involved in stress sensitivity. We examined these patterns in a sample of 12,420 young adults ages 24-32 years who participated in Wave IV of the National Longitudinal Study of Adolescent Health. Participants retrospectively reported history of physical, emotional, or sexual abuse before age 18 years. Participants with a systolic blood pressure (SBP) ≥140 mmHg or a diastolic blood pressure (DBP) ≥90 mmHg were classified as hypertensive. We used sex-stratified linear and logistic regression models to assess associations between each type of childhood maltreatment and SBP, DBP, and hypertension. We created interaction terms to assess for effect modification of any relationship between maltreatment and blood pressure by sex or SLC64A genotype. Fifteen percent of females and 31.5% of males were hypertensive. Frequent physical abuse in childhood was reported by 5%, frequent emotional abuse by 12%, and any sexual abuse by 5%. No association was observed between abuse history and blood pressure in either males or females, nor was effect modification present by SLC64A genotype. Child maltreatment exposure was not associated with blood pressure or hypertension in young adults in this study. Future studies should investigate additional critical windows for the effect of child maltreatment on cardiovascular health.

Indexed as

AdolescentAdultBlood PressureChildChild AbuseChild, PreschoolCohort StudiesFemaleGene-Environment InteractionHumansHypertensionInfantInfant, NewbornMaleRetrospective StudiesYoung AdultAdolescentChild abuse/psychologyGene–environment interactionHypertensionYoung adult

Identifiers

PMID25245501
PMCPMC4254185
OpenAlexW1982664572

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.